7082199
Tocris Bioscience™ MK6-83
TRPML channel activator
Manufacturer: Fischer Scientific
CAS Number: 1062271-24-2
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Chemical Name or Material
MK6-83
Synonym
5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide
Molecular Formula
C16H20N2O2S2
Physical Form
Solid
Purity
>98%
CAS
1062271-24-2
Solubility
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight
336.47
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ MK6-83 | -- | ₹ 23,362.50 | ||
Tocris Bioscience™ MK6-83 | -- | ₹ 96,209.00 | ||
1062271-24-2 | MK6-83 | -- | ₹ 2,581.00 - ₹ 74,315.00 |
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Description
- TRPML channel activator (EC50 = 110 nM)
- Also activates F408Δ and F465L TRPML mutants (EC50 values are 0.1 and 1.23 μM respectively)
- Restores endolysosomal trafficking and zinc homeostasis in lysosomes of mucolipidosis type IV (MLIV) mutant fibroblasts.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C