7082199

Tocris Bioscience™ MK6-83

TRPML channel activator

Manufacturer: Fischer Scientific

CAS Number: 1062271-24-2

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Chemical Name or Material

MK6-83

Synonym

5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide

Molecular Formula

C16H20N2O2S2

Physical Form

Solid

Purity

>98%

CAS

1062271-24-2

Solubility

Soluble to 100mM in DMSO and to 20mM in ethanol

Formula Weight

336.47

Product Type

Bioactive Small Molecule

Other Options

Image Product Name Manufacturer Price Range
554710
Tocris Bioscience™ MK6-83
Fischer Scientific ₹ 22,459.50
554750
Tocris Bioscience™ MK6-83
Fischer Scientific ₹ 92,490.36
AE26288
1062271-24-2 | MK6-83
A2B Chem ₹ 2,481.24 - ₹ 71,442.60

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Description

  • TRPML channel activator (EC50 = 110 nM)
  • Also activates F408Δ and F465L TRPML mutants (EC50 values are 0.1 and 1.23 μM respectively)
  • Restores endolysosomal trafficking and zinc homeostasis in lysosomes of mucolipidosis type IV (MLIV) mutant fibroblasts.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

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Chemical Name or Material:
MK6-83

Synonym:
5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide

Molecular Formula:
C16H20N2O2S2

Physical Form:
Solid

Purity:
>98%

CAS:
1062271-24-2

Solubility:
Soluble to 100mM in DMSO and to 20mM in ethanol

Formula Weight:
336.47

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Bioactive Small Molecule

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Solid

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>99%

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Soluble to 20mM in DMSO with gentle warming

Formula Weight:
454.13

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