7110774
Tocris Bioscience™ EPPTB
Trace amine 1 (TA1) receptor antagonist/inverse agonist
Manufacturer: Fischer Scientific
CAS Number: 1110781-88-8
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Chemical Name or Material
N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide
Target
Trace Amine 1 (TA1) Receptor Antagonists
Formula Weight
378.39
CAS
1110781-88-8
Molecular Formula
C20H21F3N2O2
Purity
>99%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ EPPTB | Fischer Scientific | ₹ 92,916.00 | |
| | Tocris Bioscience™ EPPTB | Fischer Scientific | ₹ 22,517.00 | |
 | Sigma Aldrich Fine Chemicals Biosciences EPPTB >=95% (HPLC) | 1110781-88-8 | MFCD21605509 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 11,230.02 | |
 | eMolecules Medchem Express / Ro 5212773 / 5mg / 680109508 / HY-110098 / / 1110781-88-8 / MFCD21605509 / 378.395 / C20H21F3N2O2 | eMolecules | ₹ 11,790.72 | |
 | 1110781-88-8 | EPPTB | A2B Chem | ₹ 4,005.00 - ₹ 2,89,428.00 |
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Description
- Trace amine 1 (TA1) receptor antagonist/inverse agonist; exhibits a higher potency at the mouse TA1 receptor than the rat and human TA1 receptors (IC50 values are 27.5, 4539 and 7487 nM, respectively)
- Blocks the TA1 receptor-mediated activation of an inwardly rectifying K+ current, which increases the firing frequency of dopamine (DA) neurons in the ventral tegmental area
- Increases DA potency at the D2 receptor
- Also displays inverse agonism, reducing basal cAMP levels in vitro (IC50 = 19 nM).
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide
Target: Trace Amine 1 (TA1) Receptor Antagonists
Formula Weight: 378.39
CAS: 1110781-88-8
Molecular Formula: C20H21F3N2O2
Purity: >99%
Chemical Name or Material:
N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide
Target:
Trace Amine 1 (TA1) Receptor Antagonists
Formula Weight:
378.39
CAS:
1110781-88-8
Molecular Formula:
C20H21F3N2O2
Purity:
>99%
Chemical Name or Material: Rho GTPase Inhibitors
Target: Small G Protein Inhibitors
Formula Weight: 324.76
CAS: 310460-39-0
Molecular Formula: C18H13ClN2O2
Purity: >98%
Chemical Name or Material:
Rho GTPase Inhibitors
Target:
Small G Protein Inhibitors
Formula Weight:
324.76
CAS:
310460-39-0
Molecular Formula:
C18H13ClN2O2
Purity:
>98%
Chemical Name or Material: 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide
Target: Compounds for Stem Cell Differentiation
Formula Weight: 387.86
CAS: 1032229-3-6
Molecular Formula: C20H22ClN3O3
Purity: >99%
Chemical Name or Material:
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide
Target:
Compounds for Stem Cell Differentiation
Formula Weight:
387.86
CAS:
1032229-3-6
Molecular Formula:
C20H22ClN3O3
Purity:
>99%
Chemical Name or Material: (1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate
Target: 5-HT2A Receptor Antagonists
Formula Weight: 386.42
CAS: 130580-02-8
Molecular Formula: C19H21FN2O2.0.5C4H4O4
Purity: >98%
Chemical Name or Material:
(1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate
Target:
5-HT2A Receptor Antagonists
Formula Weight:
386.42
CAS:
130580-02-8
Molecular Formula:
C19H21FN2O2.0.5C4H4O4
Purity:
>98%