7110784
Tocris Bioscience™ Nepicastat hydrochloride
Potent and selective dopamine β-hydroxylase (DBH) inhibitor; orally bioavailable
Manufacturer: Fischer Scientific
CAS Number: 170151-24-3
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Chemical Name or Material
5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione hydrochloride
Target
Hydroxylase Inhibitors
Formula Weight
331.81
CAS
170151-24-3
Molecular Formula
C14H15F2N3S.HCl
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Nepicastat hydrochloride | Fischer Scientific | ₹ 19,764.36 | |
| | Tocris Bioscience™ Nepicastat hydrochloride | Fischer Scientific | ₹ 82,608.18 | |
 | Apexbio Technology LLC Nepicastat (SYN-117) HCl,5mg CAS# 170151-24-3 | Apexbio Technology LLC | ₹ 5,732.52 | |
 | eMolecules Medchem Express / Nepicastat (hydrochloride) / 5mg / 446262678 / HY-13289A / / 170151-24-3 / MFCD00954638 / 331.810 / C14H16ClF2N3S | eMolecules | ₹ 8,312.15 | |
 | Sigma Aldrich Fine Chemicals Biosciences Nepicastat hydrochloride >=95% (HPLC) | 170151-24-3 | MFCD00954638 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 12,367.70 | |
 | Sigma Aldrich Fine Chemicals Biosciences Nepicastat hydrochloride >=95% (HPLC) | 170151-24-3 | MFCD00954638 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 48,769.20 | |
 | 170151-24-3 | (S)-5-(Aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1h-imidazole-2(3h)-thione hydrochloride | A2B Chem | ₹ 2,566.80 - ₹ 30,544.92 |
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Description
- Potent and selective dopamine β-hydroxylase (DBH) inhibitor (IC50 = 9 nM)
- Selective for DBH over 12 other enzymes
- Decreases noradrenaline and increases dopamine levels in tissues and plasma in hypertensive rats
- Prevents progressive left ventricular dysfunction in an in vivo heart failure model
- Also potentiates the stimulus effects of cocaine without producing cocaine-like effects in rats
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione hydrochloride
Target: Hydroxylase Inhibitors
Formula Weight: 331.81
CAS: 170151-24-3
Molecular Formula: C14H15F2N3S.HCl
Purity: >98%
Chemical Name or Material:
5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione hydrochloride
Target:
Hydroxylase Inhibitors
Formula Weight:
331.81
CAS:
170151-24-3
Molecular Formula:
C14H15F2N3S.HCl
Purity:
>98%
Chemical Name or Material: 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one
Target: Voltage-gated Potassium Channel Activators
Formula Weight: 443.18
CAS: 1259536-62-3
Molecular Formula: C18H8Cl2F4N4O
Purity: >98%
Chemical Name or Material:
5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one
Target:
Voltage-gated Potassium Channel Activators
Formula Weight:
443.18
CAS:
1259536-62-3
Molecular Formula:
C18H8Cl2F4N4O
Purity:
>98%
Chemical Name or Material: 4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile
Target: Other Transferase Inhibitors
Formula Weight: 282.36
CAS: 949912-58-7
Molecular Formula: C15H14N4S
Purity: >99%
Chemical Name or Material:
4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile
Target:
Other Transferase Inhibitors
Formula Weight:
282.36
CAS:
949912-58-7
Molecular Formula:
C15H14N4S
Purity:
>99%
Chemical Name or Material: 4-[4-(3,4-Difluorophenyl)-2-pyrimidinyl]-N-3-pyridazinyl-1-piperazinecarboxamide
Target: Fatty Acid Amide Hydrolase (FAAH) Inhibitors
Formula Weight: 397.38
CAS: 1143578-94-2
Molecular Formula: C19H17F2N7O
Purity: >98%
Chemical Name or Material:
4-[4-(3,4-Difluorophenyl)-2-pyrimidinyl]-N-3-pyridazinyl-1-piperazinecarboxamide
Target:
Fatty Acid Amide Hydrolase (FAAH) Inhibitors
Formula Weight:
397.38
CAS:
1143578-94-2
Molecular Formula:
C19H17F2N7O
Purity:
>98%