7110838
Tocris Bioscience™ BIX NHE1 inhibitor
Potent and selective NHE1 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1422252-46-7
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Chemical Name or Material
4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide hydrochloride
Target
Na+/Ca2+ Exchanger Inhibitors
Formula Weight
392.8
CAS
1422252-46-7
Molecular Formula
C16H19F3N4O2.HCl
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ BIX NHE1 inhibitor | -- | ₹ 22,250.00 | ||
Tocris Bioscience™ BIX NHE1 inhibitor | -- | ₹ 90,869.00 | ||
1422252-46-7 | BIXNHE1Inhibitor | -- | ₹ 10,235.00 - ₹ 65,415.00 |
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Description
- Potent and selective NHE1 inhibitor (IC50 = 31 nM)
- Selective for NHE1 over NHE2 and NHE3
- Prevents ischemic damage in an ischemia reperfusion injury isolated rat heart model ex vivo
- Prevents phenylephrine -induced cardiomyocyte hypertrophy in vitro , and attenuates cardiac hypertrophy and left ventricular dysfunction postinfarction in rats
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Desiccate at Room Temperature