7110838
Tocris Bioscience™ BIX NHE1 inhibitor
Potent and selective NHE1 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1422252-46-7
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Chemical Name or Material
4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide hydrochloride
Target
Na+/Ca2+ Exchanger Inhibitors
Formula Weight
392.8
CAS
1422252-46-7
Molecular Formula
C16H19F3N4O2.HCl
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ BIX NHE1 inhibitor | Fischer Scientific | ₹ 22,250.00 | |
| | Tocris Bioscience™ BIX NHE1 inhibitor | Fischer Scientific | ₹ 90,869.00 | |
 | 1422252-46-7 | BIXNHE1Inhibitor | A2B Chem | ₹ 10,235.00 - ₹ 65,415.00 |
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Description
- Potent and selective NHE1 inhibitor (IC50 = 31 nM)
- Selective for NHE1 over NHE2 and NHE3
- Prevents ischemic damage in an ischemia reperfusion injury isolated rat heart model ex vivo
- Prevents phenylephrine -induced cardiomyocyte hypertrophy in vitro , and attenuates cardiac hypertrophy and left ventricular dysfunction postinfarction in rats
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Desiccate at Room Temperature
Compare Similar Items
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Chemical Name or Material: 4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide hydrochloride
Target: Na+/Ca2+ Exchanger Inhibitors
Formula Weight: 392.8
CAS: 1422252-46-7
Molecular Formula: C16H19F3N4O2.HCl
Purity: >98%
Chemical Name or Material:
4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide hydrochloride
Target:
Na+/Ca2+ Exchanger Inhibitors
Formula Weight:
392.8
CAS:
1422252-46-7
Molecular Formula:
C16H19F3N4O2.HCl
Purity:
>98%
Chemical Name or Material: 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
Target: PERK Inhibitors
Formula Weight: 561.07
CAS: 1883548-84-2
Molecular Formula: C34H28N4O2.HCl
Purity: >98%
Chemical Name or Material:
4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
Target:
PERK Inhibitors
Formula Weight:
561.07
CAS:
1883548-84-2
Molecular Formula:
C34H28N4O2.HCl
Purity:
>98%
Chemical Name or Material: 3,4-Dihydro-N-(5-methyl-3-isoxazolyl)-α-phenyl-1(2H)-quinolineacetamide
Target: TRPM Agonists
Formula Weight: 347.41
CAS: 1031496-06-6
Molecular Formula: C21H21N3O2
Purity: >98%
Chemical Name or Material:
3,4-Dihydro-N-(5-methyl-3-isoxazolyl)-α-phenyl-1(2H)-quinolineacetamide
Target:
TRPM Agonists
Formula Weight:
347.41
CAS:
1031496-06-6
Molecular Formula:
C21H21N3O2
Purity:
>98%
Chemical Name or Material: 2-Acetylnaphtho[2,3-b]furan-4,9-dione
Target: STAT Inhibitors
Formula Weight: 240.21
CAS: 83280-65-3
Molecular Formula: C14H8O4
Purity: >98%
Chemical Name or Material:
2-Acetylnaphtho[2,3-b]furan-4,9-dione
Target:
STAT Inhibitors
Formula Weight:
240.21
CAS:
83280-65-3
Molecular Formula:
C14H8O4
Purity:
>98%