7110843
Tocris Bioscience™ NI 57
Potent and selective BRPF bromodomain inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1883548-89-7
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Chemical Name or Material
4-Cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)-2-methoxybenzene-1-sulfonamide
Target
Bromodomain Inhibitors
Formula Weight
383.42
CAS
1883548-89-7
Molecular Formula
C19H17N3O4S
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ NI 57 | Fischer Scientific | ₹ 18,361.18 | |
| | Tocris Bioscience™ NI 57 | Fischer Scientific | ₹ 74,536.45 | |
 | Medchemexpress LLC HY-19537 5mg Medchemexpress, NI-57 CAS:1883548-89-7 Purity:>98% | Medchemexpress LLC | ₹ 8,983.80 | |
 | eMolecules NI 57 | 1883548-89-7 | MFCD29081191 | 25mg | eMolecules | ₹ 44,551.09 | |
 | NI-57 | Sigma Aldrich | ₹ 11,203.88 | |
 | 1883548-89-7 | NI-57 | A2B Chem | ₹ 2,481.24 - ₹ 64,426.68 |
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Description
- Potent and selective BRPF bromodomain inhibitor (Kd values are 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively
- Exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains
- Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 4-Cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)-2-methoxybenzene-1-sulfonamide
Target: Bromodomain Inhibitors
Formula Weight: 383.42
CAS: 1883548-89-7
Molecular Formula: C19H17N3O4S
Purity: 98%
Chemical Name or Material:
4-Cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)-2-methoxybenzene-1-sulfonamide
Target:
Bromodomain Inhibitors
Formula Weight:
383.42
CAS:
1883548-89-7
Molecular Formula:
C19H17N3O4S
Purity:
98%
Chemical Name or Material: 6-(4-Methyl-1-piperazinyl)-11 H-dibenz[b,e]azepine
Target: DREADD Activators
Formula Weight: 291.39
CAS: 1977-11-3
Molecular Formula: C19H21N3
Purity: 99%
Chemical Name or Material:
6-(4-Methyl-1-piperazinyl)-11 H-dibenz[b,e]azepine
Target:
DREADD Activators
Formula Weight:
291.39
CAS:
1977-11-3
Molecular Formula:
C19H21N3
Purity:
99%
Chemical Name or Material: (2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt
Target: Protein Ser/Thr Phosphatase Inhibitors
Formula Weight: 258.66
CAS: __
Molecular Formula: C8H9ClN4.CH2O3
Purity: >98%
Chemical Name or Material:
(2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt
Target:
Protein Ser/Thr Phosphatase Inhibitors
Formula Weight:
258.66
CAS:
__
Molecular Formula:
C8H9ClN4.CH2O3
Purity:
>98%
Chemical Name or Material: 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride
Target: Nicotinic (a7) Receptor Agonists
Formula Weight: 361.66
CAS: 446031-79-4
Molecular Formula: C14H17BrN2O2.HCl
Purity: >98%
Chemical Name or Material:
4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride
Target:
Nicotinic (a7) Receptor Agonists
Formula Weight:
361.66
CAS:
446031-79-4
Molecular Formula:
C14H17BrN2O2.HCl
Purity:
>98%