7110848
Tocris Bioscience™ AZD 9272
Potent and selective mGlu5 antagonist; brain penetrant
Manufacturer: Fischer Scientific
CAS Number: 327056-26-8
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Chemical Name or Material
3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
Target
Group I mGluR Antagonists
Formula Weight
284.22
CAS
327056-26-8
Molecular Formula
C14H6F2N4O
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ AZD 9272 | Fischer Scientific | ₹ 88,063.72 | |
| | Tocris Bioscience™ AZD 9272 | Fischer Scientific | ₹ 21,164.20 | |
 | 327056-26-8 | AZD9272 | A2B Chem | ₹ 8,544.00 - ₹ 37,469.00 |
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Description
- Potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively)
- Exhibits >3900-fold selectivity for mGlu5 over other mGlu receptors
- Also selective over a panel of other targets
- Displays discriminative effects in rats
- Orally bioavailable and brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at Room Temperature
Compare Similar Items
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Chemical Name or Material: 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
Target: Group I mGluR Antagonists
Formula Weight: 284.22
CAS: 327056-26-8
Molecular Formula: C14H6F2N4O
Purity: >98%
Chemical Name or Material:
3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
Target:
Group I mGluR Antagonists
Formula Weight:
284.22
CAS:
327056-26-8
Molecular Formula:
C14H6F2N4O
Purity:
>98%
Chemical Name or Material: (2R)-2-(Acetylamino)-3-mercaptopropanamide
Target: Additional Antioxidant Compounds
Formula Weight: 162.21
CAS: 38520-57-9
Molecular Formula: C5H10N2O2S
Purity: __
Chemical Name or Material:
(2R)-2-(Acetylamino)-3-mercaptopropanamide
Target:
Additional Antioxidant Compounds
Formula Weight:
162.21
CAS:
38520-57-9
Molecular Formula:
C5H10N2O2S
Purity:
__
Chemical Name or Material: 5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
Target: Other Kinase Inhibitors
Formula Weight: 468.55
CAS: 1613724-42-7
Molecular Formula: C26H28N8O
Purity: >98%
Chemical Name or Material:
5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
Target:
Other Kinase Inhibitors
Formula Weight:
468.55
CAS:
1613724-42-7
Molecular Formula:
C26H28N8O
Purity:
>98%
Chemical Name or Material: 2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide
Target: Lipid Metabolism Inhibitors
Formula Weight: 494.35
CAS: 1267610-30-9
Molecular Formula: C20H17Cl2N5O4S
Purity: >99%
Chemical Name or Material:
2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide
Target:
Lipid Metabolism Inhibitors
Formula Weight:
494.35
CAS:
1267610-30-9
Molecular Formula:
C20H17Cl2N5O4S
Purity:
>99%