7110848

Tocris Bioscience™ AZD 9272

Potent and selective mGlu5 antagonist; brain penetrant

Manufacturer: Fischer Scientific

CAS Number: 327056-26-8

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Chemical Name or Material

3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile

Target

Group I mGluR Antagonists

Formula Weight

284.22

CAS

327056-26-8

Molecular Formula

C14H6F2N4O

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ AZD 9272
-- ₹ 88,063.72
Tocris Bioscience™ AZD 9272
-- ₹ 21,164.20
327056-26-8 | AZD9272
-- ₹ 8,544.00 - ₹ 37,469.00

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Description

  • Potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively)
  • Exhibits >3900-fold selectivity for mGlu5 over other mGlu receptors
  • Also selective over a panel of other targets
  • Displays discriminative effects in rats
  • Orally bioavailable and brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Store at Room Temperature