7110860
Tocris Bioscience™ Hydroxychloroquine sulfate
Autophagy inhibitor; also TLR9 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 747-36-4
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Chemical Name or Material
2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate
Target
Autophagy-related Compounds
Formula Weight
433.95
CAS
747-36-4
Molecular Formula
C18H28ClN3O5S
Purity
>99%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Hydroxychloroquine sulfate | Fischer Scientific | ₹ 12,431.87 | |
| | Tocris Bioscience™ Hydroxychloroquine sulfate | Fischer Scientific | ₹ 51,549.90 | |
| | 2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol, MilliporeSigma™ Supelco™ | MilliporeSigma Supelco | ₹ 24,641.28 | |
 | Selleck Chemical LLC Hydroxychloroquine Sulfate 10mg 747-36-4 HCQ | Selleck Chemical LLC | ₹ 15,092.78 | |
 | Hydroxychloroquine sulfate | Supelco | ₹ 6,007.88 | |
| | Hydroxychloroquine sulfate | Sigma Aldrich | ₹ 40,756.13 | |
| | 2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol | Sigma Aldrich | ₹ 25,103.18 | |
| | Hydroxychloroquine sulfate | Sigma Aldrich | ₹ 21,401.03 | |
 | 747-36-4 | 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol; sulfuric acid | A2B Chem | ₹ 855.60 - ₹ 63,314.40 |
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Description
- Autophagy inhibitor
- Inhibits growth and induces apoptosis of renal cancer cells in vitro
- Also inhibits TLR9
- Additionally inhibits PRC2 by inhibiting the allosteric binding of PRC2 to EED (embryonic ectoderm development) within the H3K27me3-binding pocket, and reduces H3K27me3 levels in multiple myeloma cells in vitro
- Hydroxychloroquine sulfate is an autophagy inhibitor
- Also inhibits TLR9
- Inhibits growth and induces apoptosis of renal cancer cells in vitro
- Additionally inhibits PRC2 by inhibiting the allosteric binding of PRC2 to EED (embryonic ectoderm development) within the H3K27me3-binding pocket, and reduces H3K27me3 levels in multiple myeloma cells in vitro
- Inhibits SARS-CoV-2 viral infection, in vitro (EC50 values in μM range and dependent on viral RNA copy number)
- Hydroxychloroquine improves efficacy of adeno-associated viral gene transduction in vivo and in vitro
- Also antimalarial and immunomodulator
- Tocris products are for biomedical research use only
- They are not intended for human or veterinary use.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate
Target: Autophagy-related Compounds
Formula Weight: 433.95
CAS: 747-36-4
Molecular Formula: C18H28ClN3O5S
Purity: >99%
Chemical Name or Material:
2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate
Target:
Autophagy-related Compounds
Formula Weight:
433.95
CAS:
747-36-4
Molecular Formula:
C18H28ClN3O5S
Purity:
>99%
Chemical Name or Material: 1-[(3-Methoxyphenyl)methyl]-N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-3-(4-methylphenyl)-1H-pyrazole-4-carboxamide
Target: LXR-like Receptor Antagonists
Formula Weight: 560.66
CAS: 1609564-75-1
Molecular Formula: C30H32N4O5S
Purity: >98%
Chemical Name or Material:
1-[(3-Methoxyphenyl)methyl]-N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-3-(4-methylphenyl)-1H-pyrazole-4-carboxamide
Target:
LXR-like Receptor Antagonists
Formula Weight:
560.66
CAS:
1609564-75-1
Molecular Formula:
C30H32N4O5S
Purity:
>98%
Chemical Name or Material: 3-(3-Aminopropoxy)-N-[2-[[3-[[(4-chloro-2-hydroxyphenyl)amino]carbonyl]-2-naphthalenyl]oxy]ethyl]-2-naphthalenecarboxamide hydrochloride
Target: Additional Transcription Factor Compounds
Formula Weight: 620.52
CAS: 1433286-70-4
Molecular Formula: C33H30ClN3O5.HCl
Purity: >98%
Chemical Name or Material:
3-(3-Aminopropoxy)-N-[2-[[3-[[(4-chloro-2-hydroxyphenyl)amino]carbonyl]-2-naphthalenyl]oxy]ethyl]-2-naphthalenecarboxamide hydrochloride
Target:
Additional Transcription Factor Compounds
Formula Weight:
620.52
CAS:
1433286-70-4
Molecular Formula:
C33H30ClN3O5.HCl
Purity:
>98%
Chemical Name or Material: Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate
Target: Additional Stem Cell Dedifferentiation Products
Formula Weight: 282.75
CAS: 165682-93-9
Molecular Formula: C12H11ClN2O2S
Purity: >98%
Chemical Name or Material:
Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate
Target:
Additional Stem Cell Dedifferentiation Products
Formula Weight:
282.75
CAS:
165682-93-9
Molecular Formula:
C12H11ClN2O2S
Purity:
>98%