7110870
Tocris Bioscience™ SB 332235
Potent CXCR2 antagonist
Manufacturer: Fischer Scientific
CAS Number: 276702-15-9
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Chemical Name or Material
6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
Target
Chemokine Receptor Antagonists
Formula Weight
410.66
CAS
276702-15-9
Molecular Formula
C13H10Cl3N3O4S
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ SB 332235 | Fischer Scientific | ₹ 28,079.50 | |
| | Tocris Bioscience™ SB 332235 | Fischer Scientific | ₹ 1,14,543.00 | |
 | 276702-15-9 | SB-332235 | A2B Chem | ₹ 3,560.00 - ₹ 42,720.00 |
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Description
- Potent CXCR2 antagonist (IC50 = 7.7 nM)
- Exhibits 285-fold selectivity for CXCR2 over CXCR1
- Reduces leukocyte numbers in synovial fluid in acute and chronic rabbit arthritis models
- Also reduces synovial fluid eicosanoid and cytokine levels in a rabbit chronic arthritis model
- Inhibits proliferation of AML cell lines in vitro .
SAFETY INFORMATION
- Recommended Storage : Store at Room Temperature
Compare Similar Items
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Chemical Name or Material: 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
Target: Chemokine Receptor Antagonists
Formula Weight: 410.66
CAS: 276702-15-9
Molecular Formula: C13H10Cl3N3O4S
Purity: >98%
Chemical Name or Material:
6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
Target:
Chemokine Receptor Antagonists
Formula Weight:
410.66
CAS:
276702-15-9
Molecular Formula:
C13H10Cl3N3O4S
Purity:
>98%
Chemical Name or Material: 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Target: Additional RTK Inhibitors
Formula Weight: 366.41
CAS: 870483-87-7
Molecular Formula: C20H22N4O3
Purity: >99%
Chemical Name or Material:
5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Target:
Additional RTK Inhibitors
Formula Weight:
366.41
CAS:
870483-87-7
Molecular Formula:
C20H22N4O3
Purity:
>99%
Chemical Name or Material: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid
Target: PPAR delta Receptor Agonists
Formula Weight: 453.5
CAS: 317318-70-0
Molecular Formula: C21H18F3NO3S2
Purity: >98%
Chemical Name or Material:
2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid
Target:
PPAR delta Receptor Agonists
Formula Weight:
453.5
CAS:
317318-70-0
Molecular Formula:
C21H18F3NO3S2
Purity:
>98%
Chemical Name or Material: N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride
Target: TRPV Antagonists
Formula Weight: 536.95
CAS: 2109450-40-8
Molecular Formula: C21H23F3N4O5S.HCl
Purity: >99%
Chemical Name or Material:
N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride
Target:
TRPV Antagonists
Formula Weight:
536.95
CAS:
2109450-40-8
Molecular Formula:
C21H23F3N4O5S.HCl
Purity:
>99%