7110870
Tocris Bioscience™ SB 332235
Potent CXCR2 antagonist
Manufacturer: Fischer Scientific
CAS Number: 276702-15-9
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Chemical Name or Material
6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
Target
Chemokine Receptor Antagonists
Formula Weight
410.66
CAS
276702-15-9
Molecular Formula
C13H10Cl3N3O4S
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ SB 332235 | -- | ₹ 28,079.50 | ||
Tocris Bioscience™ SB 332235 | -- | ₹ 1,14,543.00 | ||
276702-15-9 | SB-332235 | -- | ₹ 3,560.00 - ₹ 42,720.00 |
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Description
- Potent CXCR2 antagonist (IC50 = 7.7 nM)
- Exhibits 285-fold selectivity for CXCR2 over CXCR1
- Reduces leukocyte numbers in synovial fluid in acute and chronic rabbit arthritis models
- Also reduces synovial fluid eicosanoid and cytokine levels in a rabbit chronic arthritis model
- Inhibits proliferation of AML cell lines in vitro .
SAFETY INFORMATION
- Recommended Storage : Store at Room Temperature