7110870

Tocris Bioscience™ SB 332235

Potent CXCR2 antagonist

Manufacturer: Fischer Scientific

CAS Number: 276702-15-9

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Chemical Name or Material

6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide

Target

Chemokine Receptor Antagonists

Formula Weight

410.66

CAS

276702-15-9

Molecular Formula

C13H10Cl3N3O4S

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
56-711-0
Tocris Bioscience™ SB 332235
Fischer Scientific ₹ 26,994.18
56-715-0
Tocris Bioscience™ SB 332235
Fischer Scientific ₹ 1,10,115.72
AF34671
276702-15-9 | SB-332235
A2B Chem ₹ 3,422.40 - ₹ 41,068.80

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Description

  • Potent CXCR2 antagonist (IC50 = 7.7 nM)
  • Exhibits 285-fold selectivity for CXCR2 over CXCR1
  • Reduces leukocyte numbers in synovial fluid in acute and chronic rabbit arthritis models
  • Also reduces synovial fluid eicosanoid and cytokine levels in a rabbit chronic arthritis model
  • Inhibits proliferation of AML cell lines in vitro .

SAFETY INFORMATION

  • Recommended Storage : Store at Room Temperature

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Potent CXCR2 antagonist...


Chemical Name or Material:
6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide

Target:
Chemokine Receptor Antagonists

Formula Weight:
410.66

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276702-15-9

Molecular Formula:
C13H10Cl3N3O4S

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>98%

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