7110896
Tocris Bioscience™ PF 06260933 dihydrochloride
MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK
Manufacturer: Fischer Scientific
CAS Number: 1883548-86-4
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Chemical Name or Material
5-(4-Chlorophenyl)-[3,3 '-bipyridine]-6,6 '-diamine dihydrochloride
Synonym
EC 2.7.11, EC 2.7.11.1, FLH21957, FLJ10410, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, HGKFLJ20373, HPK/GCK-like kinase HGK, KIAA0687, MAP4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, mitogen-activa
Molecular Formula
C16H13ClN40.2 HCl
Purity
98%
CAS
1883548-86-4
Target
HGK/MAP4K4
Formula Weight
369.68
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ PF 06260933 dihydrochloride | Fischer Scientific | ₹ 22,887.30 | |
| | Tocris Bioscience™ PF 06260933 dihydrochloride | Fischer Scientific | ₹ 95,228.28 | |
 | 1883548-86-4 | PF06260933dihydrochloride | A2B Chem | ₹ 12,834.00 - ₹ 39,443.16 |
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Description
- MAP4K4 (HGK) inhibitor (IC50 = 140 nM)
- Also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively)
- Improves fasting hyperglycemia in mice
- Orally active.
SAFETY INFORMATION
- Recommended Storage : Desiccate at Room Temperature
Compare Similar Items
Show Difference
Chemical Name or Material: 5-(4-Chlorophenyl)-[3,3 '-bipyridine]-6,6 '-diamine dihydrochloride
Synonym: EC 2.7.11, EC 2.7.11.1, FLH21957, FLJ10410, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, HGKFLJ20373, HPK/GCK-like kinase HGK, KIAA0687, MAP4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, mitogen-activa
Molecular Formula: C16H13ClN40.2 HCl
Purity: 98%
CAS: 1883548-86-4
Target: HGK/MAP4K4
Formula Weight: 369.68
Chemical Name or Material:
5-(4-Chlorophenyl)-[3,3 '-bipyridine]-6,6 '-diamine dihydrochloride
Synonym:
EC 2.7.11, EC 2.7.11.1, FLH21957, FLJ10410, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, HGKFLJ20373, HPK/GCK-like kinase HGK, KIAA0687, MAP4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, mitogen-activa
Molecular Formula:
C16H13ClN40.2 HCl
Purity:
98%
CAS:
1883548-86-4
Target:
HGK/MAP4K4
Formula Weight:
369.68
Chemical Name or Material: N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride
Synonym: __
Molecular Formula: C38H38N4O6.2HCl
Purity: >98%
CAS: 1992047-62-7
Target: Multidrug Transporter Inhibitors
Formula Weight: 719.66
Chemical Name or Material:
N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride
Synonym:
__
Molecular Formula:
C38H38N4O6.2HCl
Purity:
>98%
CAS:
1992047-62-7
Target:
Multidrug Transporter Inhibitors
Formula Weight:
719.66
Chemical Name or Material: 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine
Synonym: __
Molecular Formula: C21H20N2OS3
Purity: >98%
CAS: 459147-39-8
Target: Dehydrogenase Inhibitors
Formula Weight: 412.59
Chemical Name or Material:
2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine
Synonym:
__
Molecular Formula:
C21H20N2OS3
Purity:
>98%
CAS:
459147-39-8
Target:
Dehydrogenase Inhibitors
Formula Weight:
412.59
Chemical Name or Material: (-)-(R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
Synonym: __
Molecular Formula: C20H21FN2O.C2H2O4
Purity: >98%
CAS: 219861-53-7
Target: 5-HT Transporter Inhibitors
Formula Weight: 414.43
Chemical Name or Material:
(-)-(R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
Synonym:
__
Molecular Formula:
C20H21FN2O.C2H2O4
Purity:
>98%
CAS:
219861-53-7
Target:
5-HT Transporter Inhibitors
Formula Weight:
414.43