7110926
Tocris Bioscience™ JX 06
Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 729-46-4
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Chemical Name or Material
Bis(morpholinothiocarbonyl) disulfide
Target
PDK-1 Inhibitors
Formula Weight
324.51
CAS
729-46-4
Molecular Formula
C10H16N2O2S4
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ JX 06 | Fischer Scientific | ₹ 11,267.40 | |
| | Tocris Bioscience™ JX 06 | Fischer Scientific | ₹ 46,636.00 | |
 | 729-46-4 | Morpholine,4,4'-(dithiodicarbonothioyl)bis- | A2B Chem | ₹ 4,539.00 - ₹ 33,197.00 |
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Description
- Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor (IC50 values are 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively)
- Exhibits selectivity for PDK1/2/3 over PDK4 and a panel of 323 other kinases
- Suppresses A549 lung cancer cell proliferation in vitro
- Reduces tumor volume of A549 xenografts in mice.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: Bis(morpholinothiocarbonyl) disulfide
Target: PDK-1 Inhibitors
Formula Weight: 324.51
CAS: 729-46-4
Molecular Formula: C10H16N2O2S4
Purity: >98%
Chemical Name or Material:
Bis(morpholinothiocarbonyl) disulfide
Target:
PDK-1 Inhibitors
Formula Weight:
324.51
CAS:
729-46-4
Molecular Formula:
C10H16N2O2S4
Purity:
>98%
Chemical Name or Material: Ethyl 5-[[[[3′-(Methylsulfonyl)[1,1′-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate
Target: LXR-like Receptor Antagonists
Formula Weight: 595.73
CAS: 1416153-62-2
Molecular Formula: C31H33NO7S2
Purity: >98%
Chemical Name or Material:
Ethyl 5-[[[[3′-(Methylsulfonyl)[1,1′-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate
Target:
LXR-like Receptor Antagonists
Formula Weight:
595.73
CAS:
1416153-62-2
Molecular Formula:
C31H33NO7S2
Purity:
>98%
Chemical Name or Material: Ethyl 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate
Target: Nuclear Receptor Agonists
Formula Weight: 437.94
CAS: 1379686-30-2
Molecular Formula: C20H24ClN3O4S
Purity: >98%
Chemical Name or Material:
Ethyl 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate
Target:
Nuclear Receptor Agonists
Formula Weight:
437.94
CAS:
1379686-30-2
Molecular Formula:
C20H24ClN3O4S
Purity:
>98%
Chemical Name or Material: (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
Target: Catechol O-Methyltransferase (COMT) Inhibitors
Formula Weight: 273.24
CAS: 134308-13-7
Molecular Formula: C14H11NO5
Purity: >99%
Chemical Name or Material:
(3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
Target:
Catechol O-Methyltransferase (COMT) Inhibitors
Formula Weight:
273.24
CAS:
134308-13-7
Molecular Formula:
C14H11NO5
Purity:
>99%