7112887
Tocris Bioscience™ AAQ Chloride
Photoswitchable Kv channel blocker
Manufacturer: Fischer Scientific
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Chemical Name or Material
N,N,N-Triethyl-2-oxo-2-[[4-[2-[4-[(1-oxo-2-propen-1-yl)amino]phenyl]diazenyl]phenylamino]ethanaminium chloride
Solubility
Soluble to 20mM in DMSO
Molecular Formula
C23H30ClN5O2
Formula Weight
Observed MW: 443.97
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Description
- Photoswitchable Kv channel blocker (IC50 values are 2 and 64 μM at 500 nm and 380 nm respectively)
- Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm
- Exhibits minimal activity at Nav1.2 and L-type Ca2+ channels
- Stimulates action potential firing of hippocampal neurons in vitro at 500 nm and restores visual responsiveness in blind mice at 380 nm.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N,N,N-Triethyl-2-oxo-2-[[4-[2-[4-[(1-oxo-2-propen-1-yl)amino]phenyl]diazenyl]phenylamino]ethanaminium chloride
Solubility: Soluble to 20mM in DMSO
Molecular Formula: C23H30ClN5O2
Formula Weight: Observed MW: 443.97
Chemical Name or Material:
N,N,N-Triethyl-2-oxo-2-[[4-[2-[4-[(1-oxo-2-propen-1-yl)amino]phenyl]diazenyl]phenylamino]ethanaminium chloride
Solubility:
Soluble to 20mM in DMSO
Molecular Formula:
C23H30ClN5O2
Formula Weight:
Observed MW: 443.97
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