7161661
Tocris Bioscience™ PKUMDL WQ 2101
Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)
Manufacturer: Fischer Scientific
CAS Number: 304481-72-9
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Chemical Name or Material
2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide
Molecular Formula
C14H11N3O6
Purity
98%
CAS
304481-72-9
Formula Weight
317.25
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ PKUMDL WQ 2101 | Fischer Scientific | ₹ 9,389.50 | |
| | Tocris Bioscience™ PKUMDL WQ 2101 | Fischer Scientific | ₹ 36,089.50 | |
 | eMolecules Medchem Express / PKUMDL-WQ-2101 / 5mg / 791206339 / HY-123269 / / 304481-72-9 / [null] / 317.257 / C14H11N3O6 | eMolecules | ₹ 6,550.40 |
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Description
- Description Negative allosteric modulator of phosphoglycerate dehydrogenase (PHGDH) (IC50 = 34.8 μM) Exhibits antitumor activity in vitro in breast cancer cells lines overexpressing PHGDH (EC50 values are 7.7 and 10.8 μM in MDA-MB-468 and HCC-70 cells, respectively) Inhibits growth of MDA-MB-468 xenografts in mice
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide
Molecular Formula: C14H11N3O6
Purity: 98%
CAS: 304481-72-9
Formula Weight: 317.25
Chemical Name or Material:
2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide
Molecular Formula:
C14H11N3O6
Purity:
98%
CAS:
304481-72-9
Formula Weight:
317.25
Chemical Name or Material: 2-Chloro-4-[5-[[2-[(ethylamino)thioxomethyl]hydrazinylidene]methyl]-2-furanyl]benzoic acid
Molecular Formula: C15H14ClN3O3S
Purity: 98%
CAS: 592474-91-4
Formula Weight: 351.81
Chemical Name or Material:
2-Chloro-4-[5-[[2-[(ethylamino)thioxomethyl]hydrazinylidene]methyl]-2-furanyl]benzoic acid
Molecular Formula:
C15H14ClN3O3S
Purity:
98%
CAS:
592474-91-4
Formula Weight:
351.81
Chemical Name or Material: N-(3 S)-1-Azabicyclo[2.2.2 ]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate
Molecular Formula: C16H22N2O3.CF3CO2H
Purity: 98%
CAS: 1336913-03-1
Formula Weight: 404.38
Chemical Name or Material:
N-(3 S)-1-Azabicyclo[2.2.2 ]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate
Molecular Formula:
C16H22N2O3.CF3CO2H
Purity:
98%
CAS:
1336913-03-1
Formula Weight:
404.38
Chemical Name or Material: 3-[6-(Dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine hydrochloride
Molecular Formula: C22H32N6.HCl
Purity: 98%
CAS: 195055-66-4
Formula Weight: 416.99
Chemical Name or Material:
3-[6-(Dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine hydrochloride
Molecular Formula:
C22H32N6.HCl
Purity:
98%
CAS:
195055-66-4
Formula Weight:
416.99