7199107
Tocris™ Palonosetron hydrochloride
Highly potent and high affinity 5-HT3 antagonist
Manufacturer: Fischer Scientific
CAS Number: 135729-62-3
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Chemical Name or Material
(3 AS)-2-[(3 S)-1-azabicyclo[2.2.2 ]oct-3-yl]-2,3,3 A,4,5,6-hexahydro-1 H-benz[de]isoquinolin-1-one hydrochloride
Target
5-HT3 Receptor Antagonists
Purity
98%
CAS
135729-62-3
Molecular Formula
C19H24N2O.HCl
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Description
- Highly potent and high affinity 5-HT3 antagonist (IC50 = 0.24 nM for 5-HT3A; pKi = 10.4)
- Displays a slow dissociation rate
- Inhibits 5-HT-induced enhancement of cellular response to substance P (Cat
- No
- 1156) in vitro
- Inhibits cisplatin (Cat
- No
- 2251)-induced enhancement of substance P response in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: (3 AS)-2-[(3 S)-1-azabicyclo[2.2.2 ]oct-3-yl]-2,3,3 A,4,5,6-hexahydro-1 H-benz[de]isoquinolin-1-one hydrochloride
Target: 5-HT3 Receptor Antagonists
Purity: 98%
CAS: 135729-62-3
Molecular Formula: C19H24N2O.HCl
Chemical Name or Material:
(3 AS)-2-[(3 S)-1-azabicyclo[2.2.2 ]oct-3-yl]-2,3,3 A,4,5,6-hexahydro-1 H-benz[de]isoquinolin-1-one hydrochloride
Target:
5-HT3 Receptor Antagonists
Purity:
98%
CAS:
135729-62-3
Molecular Formula:
C19H24N2O.HCl
Chemical Name or Material: (2 Z)-2 [[3-[(4-Chlorophenyl)methoxy]phenyl]methylene]-6,7-dihydro-5 H-imidazo[2,1-b][1,3 ]thiazin-3(2 H)-one
Target: Additional Cannabinoid-related Compounds
Purity: 98%
CAS: 1627710-30-8
Molecular Formula: C20H17ClN2O2S
Chemical Name or Material:
(2 Z)-2 [[3-[(4-Chlorophenyl)methoxy]phenyl]methylene]-6,7-dihydro-5 H-imidazo[2,1-b][1,3 ]thiazin-3(2 H)-one
Target:
Additional Cannabinoid-related Compounds
Purity:
98%
CAS:
1627710-30-8
Molecular Formula:
C20H17ClN2O2S
Chemical Name or Material: N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine
Target: PDGF Receptor Inhibitors
Purity: 98%
CAS: 627518-40-5
Molecular Formula: C18H16FN3O2
Chemical Name or Material:
N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine
Target:
PDGF Receptor Inhibitors
Purity:
98%
CAS:
627518-40-5
Molecular Formula:
C18H16FN3O2
Chemical Name or Material: N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide
Target: RIP Kinase Inhibitors
Purity: 98%
CAS: 355406-76-7
Molecular Formula: C26H21FN2O3
Chemical Name or Material:
N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide
Target:
RIP Kinase Inhibitors
Purity:
98%
CAS:
355406-76-7
Molecular Formula:
C26H21FN2O3