7250118
Tocris Bioscience™ Capzimin dimer
Selective proteasome inhibitor
Manufacturer: Fischer Scientific
CAS Number: 2084868-04-0
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Chemical Name or Material
8,8 '-Dithiobis[N-[2-(2-thiazolyl)ethyl]-3-quinolinecarboxamide]
Target
Proteasome Inhibitors
Purity
0.98
CAS
2084868-04-0
Molecular Formula
C30H24N6O2S4
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Capzimin dimer | Fischer Scientific | ₹ 17,765.68 | |
| | Tocris Bioscience™ Capzimin dimer | Fischer Scientific | ₹ 74,734.95 | |
 | eMolecules Medchem Express / Capzimin / 5mg / 446259818 / HY-110404 / / 2084868-04-0 / [null] / 628.800 / C30H24N6O2S4 | eMolecules | ₹ 18,891.65 | |
 | 2084868-04-0 | Capzimin | A2B Chem | ₹ 7,015.92 - ₹ 56,127.36 |
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Description
- Capzimin dimer is a specific inhibitor of proteasome isopeptidase Rpn11 (IC50 = 2.1 μM and 3.8 μM, in 293T and A549 cell lines, respectively)
- It exhibits 80-fold selectivity for Rpn11 over Csn5, ten-fold over AMSH and six-fold over BRCC36 (IC50 = 30 μM, 4.5 μM, and 2.3 μM, respectively)
- Capzimin dimer blocks proliferation of cancer cells.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 8,8 '-Dithiobis[N-[2-(2-thiazolyl)ethyl]-3-quinolinecarboxamide]
Target: Proteasome Inhibitors
Purity: 0.98
CAS: 2084868-04-0
Molecular Formula: C30H24N6O2S4
Chemical Name or Material:
8,8 '-Dithiobis[N-[2-(2-thiazolyl)ethyl]-3-quinolinecarboxamide]
Target:
Proteasome Inhibitors
Purity:
0.98
CAS:
2084868-04-0
Molecular Formula:
C30H24N6O2S4
Chemical Name or Material: 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide
Target: PPAR gamma/NR1C3
Purity: 0.98
CAS: 315224-26-1
Molecular Formula: C21H12Cl4N2O3S
Chemical Name or Material:
2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide
Target:
PPAR gamma/NR1C3
Purity:
0.98
CAS:
315224-26-1
Molecular Formula:
C21H12Cl4N2O3S
Chemical Name or Material: 3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid
Target: Antiviral Compounds
Purity: 0.98
CAS: 1225177-95-6
Molecular Formula: C16H14N4O2
Chemical Name or Material:
3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid
Target:
Antiviral Compounds
Purity:
0.98
CAS:
1225177-95-6
Molecular Formula:
C16H14N4O2
Chemical Name or Material: N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide
Target: MEK Inhibitors
Purity: 0.98
CAS: 871700-17-3
Molecular Formula: C26H23FIN5O4
Chemical Name or Material:
N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide
Target:
MEK Inhibitors
Purity:
0.98
CAS:
871700-17-3
Molecular Formula:
C26H23FIN5O4