78-202
Tocris Bioscience™ CU-76
Manufacturer: Tocris Bioscience™
CAS Number: 2400954-58-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 78-202-Each-of-1 | In Stock | ₹ 17,043.50 |
78-202 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,043.50
GST (18%): ₹ 3,067.83
Total Price: ₹ 20,111.33
Chemical Name or Material
Methyl 4-amino-6-[(3,5-difluoro-4-iodophenyl)amino]-1,3,5-triazine-2-carboxylate
Quantity
2 mg
Molecular Formula
C11H8F2IN5O2
CAS
2400954-58-5
Target
STING/TMEM173
Purity
0.98
Related Products
Description
- CU-76 is a selective cyclic GMP-AMP synthase (cGAS) inhibitor (IC50 = 0.24 μM)
- It specifically inhibits cGAS-STING pathway and has no effect on other nucleic acid sensing pathways such as the RIG-I-MAVS or Toll-like receptor pathways
- CU-76 reduces DNA-induced IFN regulatory factor 3 (IRF3) dimerization in a dose-dependent manner, and it decreases production of IFN-β in THP-1 cells stimulated with interferon-stimulatory DNA.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: Methyl 4-amino-6-[(3,5-difluoro-4-iodophenyl)amino]-1,3,5-triazine-2-carboxylate
Quantity: 2 mg
Molecular Formula: C11H8F2IN5O2
CAS: 2400954-58-5
Target: STING/TMEM173
Purity: 0.98
Chemical Name or Material:
Methyl 4-amino-6-[(3,5-difluoro-4-iodophenyl)amino]-1,3,5-triazine-2-carboxylate
Quantity:
2 mg
Molecular Formula:
C11H8F2IN5O2
CAS:
2400954-58-5
Target:
STING/TMEM173
Purity:
0.98
Chemical Name or Material: __
Quantity: 4 x 1 mL
Molecular Formula: __
CAS: __
Target: __
Purity: __
Chemical Name or Material:
__
Quantity:
4 x 1 mL
Molecular Formula:
__
CAS:
__
Target:
__
Purity:
__
Chemical Name or Material: __
Quantity: 10 mL
Molecular Formula: __
CAS: __
Target: __
Purity: __
Chemical Name or Material:
__
Quantity:
10 mL
Molecular Formula:
__
CAS:
__
Target:
__
Purity:
__
Chemical Name or Material: 2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
Quantity: 10 mg
Molecular Formula: C23H22Cl2N2O3S
CAS: 1035072-16-2
Target: Glutathione Peroxidase 4/GPX4
Purity: 0.98
Chemical Name or Material:
2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
Quantity:
10 mg
Molecular Formula:
C23H22Cl2N2O3S
CAS:
1035072-16-2
Target:
Glutathione Peroxidase 4/GPX4
Purity:
0.98