78-521-0
Tocris Bioscience™ EM12-SO2F
Manufacturer: Tocris Bioscience™
CAS Number: 2803819-61-4
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 78-521-0-Each-of-1 | In Stock | ₹ 12,346.31 |
78-521-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,346.31
GST (18%): ₹ 2,222.336
Total Price: ₹ 14,568.646
Chemical Name or Material
2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-3-oxo-1H-isoindole-5-sulfonyl fluoride
Quantity
10 mg
Molecular Formula
C13H11FN2O5S
CAS
2803819-61-4
Target
CRBN
Purity
95%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | EM12-SO2F | ChemScene | ₹ 6,417.00 - ₹ 72,298.20 | |
 | 2803819-61-4 | 2-(2,6-dioxopiperidin-3-yl)-3-oxoisoindoline-5-sulfonyl fluoride | A2B Chem | ₹ 5,818.08 - ₹ 37,646.40 |
Related Products
Description
- EM12-SO2F is a potent covalent Cereblon (CRBN) inhibitor (IC50 = 0.88 nM)
- Binds to a histidine residue (His353) in the IMiD binding pocket of CRBN and blocks the recruitment of its substrates
- EM12-SO2F prevents Lenalidomide (Cat
- No
- 6305)-induced degradation of the zinc finger transcription factor IKZF1 in MOLT4 cells
- It complements CRBN based PROTAC and genetic methods to validate CRBN-mediated degradation.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Show Difference
Chemical Name or Material: 2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-3-oxo-1H-isoindole-5-sulfonyl fluoride
Quantity: 10 mg
Molecular Formula: C13H11FN2O5S
CAS: 2803819-61-4
Target: CRBN
Purity: 95%
Chemical Name or Material:
2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-3-oxo-1H-isoindole-5-sulfonyl fluoride
Quantity:
10 mg
Molecular Formula:
C13H11FN2O5S
CAS:
2803819-61-4
Target:
CRBN
Purity:
95%
Chemical Name or Material: __
Quantity: 100 μg
Molecular Formula: __
CAS: __
Target: __
Purity: __
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Quantity:
100 μg
Molecular Formula:
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CAS:
__
Target:
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Purity:
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Chemical Name or Material: tert-Butyl (1-((R)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
Quantity: 5 mg
Molecular Formula: C31H39N5O7
CAS: __
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tert-Butyl (1-((R)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
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5 mg
Molecular Formula:
C31H39N5O7
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Chemical Name or Material: Poly[imino(1,2-ethanediyl)] hydrochloride
Quantity: 100 mg
Molecular Formula: __
CAS: 49553-93-7
Target: Transfection Reagent
Purity: __
Chemical Name or Material:
Poly[imino(1,2-ethanediyl)] hydrochloride
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