901494

N-Methylated pomalidomide

≥98%

Manufacturer: Sigma Aldrich

CAS Number: 1352827-50-9

Synonym(S): 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione, E3 Ligase ligand methylated negative control, Ligand for PROTAC® research

Select a Size

Pack Size SKU Availability Price
25 MG 901494-25-MG In Stock ₹ 31,710.00

901494 - 25 MG

₹ 31,710.00

In Stock

Quantity

1

Base Price: ₹ 31,710.00

GST (18%): ₹ 5,707.80

Total Price: ₹ 37,417.80

ligand

N-Methylated Pomalidomide

Quality Level

100

Assay

≥98%

form

powder or crystals

reaction suitability

reagent type: ligand

shipped in

wet ice

storage temp.

2-8°C

SMILES string

O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3N)=O)N(C)C1=O

Other Options

Image Product Name Manufacturer Price Range
77-165-0
Tocris Bioscience™ N-methylated pomalidomide
Tocris Bioscience™ ₹ 23,956.80
50-186-3182
Sigma Aldrich Fine Chemicals Biosciences N-Methylated pomalidomide >=98% | 1352827-50-9 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 45,278.35
CS-0642323
Pomalidomide-methyl
ChemScene ₹ 5,732.52 - ₹ 26,095.80
BG29767
1352827-50-9 | 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
A2B Chem ₹ 4,021.32 - ₹ 18,309.84

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Description

  • Application: N-Methylated pomalidomide is a ligand used as a negative control for pomalidomide (P0018) in the recruitment of the Cereblon (CRBN) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.
  • Other Notes: Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationPortal: Building PROTAC® Degraders for Targeted Protein DegradationHijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4Targeted Protein Degradation by Small MoleculesSmall-Molecule PROTACS: New Approaches to Protein Degradation
  • Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

901494

≥98%...


ligand:
N-Methylated Pomalidomide

Quality Level:
100

Assay:
≥98%

form:
powder or crystals

reaction suitability:
reagent type: ligand

shipped in:
wet ice

storage temp.:
2-8°C

SMILES string:
O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3N)=O)N(C)C1=O

Img

Sigma Aldrich

901495

≥95%...


ligand:
pomalidomide

Quality Level:
100

Assay:
≥95%

form:
powder or crystals

reaction suitability:
reactivity: carboxyl reactivereagent type: ligand-linker conjugate

shipped in:
wet ice

storage temp.:
2-8°C

SMILES string:
O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3NC(COCCOCCOCCN)=O)=O)NC1=O.Cl

Img

Sigma Aldrich

901496

≥98%...


ligand:
pomalidomide

Quality Level:
100

Assay:
≥98%

form:
powder or crystals

reaction suitability:
reactivity: amine reactivereagent type: ligand-linker conjugate

shipped in:
__

storage temp.:
2-8°C

SMILES string:
O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCC(O)=O)=O

Img

Sigma Aldrich

901500

≥95%...


ligand:
pomalidomide

Quality Level:
100

Assay:
≥95%

form:
powder or crystals

reaction suitability:
reactivity: amine reactivereagent type: ligand-linker conjugate

shipped in:
wet ice

storage temp.:
2-8°C

SMILES string:
O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3NCCCC(O)=O)=O)NC1=O