908401
1-Methyl-7-nitroisatoic anhydride
Manufacturer: Sigma Aldrich
CAS Number: 73043-80-8
Synonym(S): 1-Methyl-7-nitro-2H-3,1-benzoxazine-2,4(1H)-dione, 1-methyl-7-nitro-2H-3,1-Benzoxazine-2,4(1H)-dione, 1M7, RNA SHAPE probe, Reagent for RNA SHAPE-MaP
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 250 MG | 908401-250-MG | In Stock | ₹ 21,290.00 |
| 1 G | 908401-1-G | In Stock | ₹ 52,000.00 |
908401 - 250 MG
In Stock
Quantity
1
Base Price: ₹ 21,290.00
GST (18%): ₹ 3,832.20
Total Price: ₹ 25,122.20
form
powder
mp
204.5 °C
storage temp.
2-8°C
InChI
1S/C9H6N2O5/c1-10-7-4-5(11(14)15)2-3-6(7)8(12)16-9(10)13/h2-4H,1H3
InChI key
MULNCJWAVSDEKJ-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ 1M7 | Tocris Bioscience™ | ₹ 31,817.50 | |
 | Sigma Aldrich Fine Chemicals Biosciences 1-Methyl-7-nitroisatoic anhydride | 73043-80-8 | MFCD18432729 | 250mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 33,361.65 | |
 | 7-nitro-1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione | Aaron Chemicals LLC | ₹ 623.00 - ₹ 26,878.00 |
Related Products
Description
- Application: 1-Methyl-7-nitroisatoic anhydride (1M7) is used as an in vivo SHAPE-MaP reagent for live cell RNA structure analysis at single nucleotide resolution. SHAPE -- or selective 2′-hydroxyl acylation analyzed by primer extension -- uses small, electrophilic chemical probes such as 1M7 to react with the 2′-hydroxyl group and provides insight to RNA structure. When combined with mutational profiling (MaP), quantitative nucleotide measurements are possible for entire transciptomes. Together, these methods deepen the understanding of RNA interactions and regions that may be exploited for design of RNA-targeting small-molecule drugs.
- Other Notes: Pervasive Regulatory Functions of mRNA Structure Revealed by High-Resolution SHAPE ProbingSnapShot: RNA Structure Probing TechnologiesDetection of RNA-Protein Interactions in Living Cells with SHAPEStandardization of RNA Chemical Mapping ExperimentsIn-cell RNA structure probing with SHAPE-MaPA Fast-Acting Reagent for Accurate Analysis of RNA Secondary and Tertiary Structure by SHAPE Chemistry
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
form: powder
mp: 204.5 °C
storage temp.: 2-8°C
InChI: 1S/C9H6N2O5/c1-10-7-4-5(11(14)15)2-3-6(7)8(12)16-9(10)13/h2-4H,1H3
InChI key: MULNCJWAVSDEKJ-UHFFFAOYSA-N
form:
powder
mp:
204.5 °C
storage temp.:
2-8°C
InChI:
1S/C9H6N2O5/c1-10-7-4-5(11(14)15)2-3-6(7)8(12)16-9(10)13/h2-4H,1H3
InChI key:
MULNCJWAVSDEKJ-UHFFFAOYSA-N
form: powder
mp: __
storage temp.: −20°C
InChI: 1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
InChI key: VBICKXHEKHSIBG-UHFFFAOYSA-N
form:
powder
mp:
__
storage temp.:
−20°C
InChI:
1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
InChI key:
VBICKXHEKHSIBG-UHFFFAOYSA-N
form: (Powder or Solid or Chunks)
mp: __
storage temp.: 2-8°C
InChI: __
InChI key: __
form:
(Powder or Solid or Chunks)
mp:
__
storage temp.:
2-8°C
InChI:
__
InChI key:
__
form: powder or crystals
mp: 46-48 °C
storage temp.: −20°C
InChI: __
InChI key: __
form:
powder or crystals
mp:
46-48 °C
storage temp.:
−20°C
InChI:
__
InChI key:
__