SML2684
dTRIM24
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 2170695-14-2
Synonym(S): (2S,4R)-1-((S)-15-(tert-Butyl)-1-(3-(N-(1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)phenyl)-1,13-dioxo-5,8,11-trioxa-2,14-diazahexadecan-16-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | SML2684-1-MG | In Stock | ₹ 11,745.13 |
| 5 MG | SML2684-5-MG | In Stock | ₹ 35,754.98 |
SML2684 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 11,745.13
GST (18%): ₹ 2,114.123
Total Price: ₹ 13,859.253
ligand
VL-269
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
O=C(N1C)N(C)C2=C1C=C(OC3=CC=CC(OCCC)=C3)C(NS(C4=CC(C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N5C[C@H](O)C[C@H]5C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)=O)=O)=CC=C4)(=O)=O)=C2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris™ dTRIM 24 | Tocris™ | ₹ 46,636.00 | |
 | Medchemexpress LLC HY-111519 5mg , dTRIM24 CAS:2170695-14-2 Purity:>98% | Medchemexpress LLC | ₹ 32,707.50 | |
 | 2170695-14-2 | DTRIM24 | A2B Chem | ₹ 8,900.00 - ₹ 51,620.00 |
Description
- Biochem/physiol Actions: dTRIM24, a conjugate of IACS-9571 a TRIM24 bromodomain ligand and VL-269 a VHL E3 ubiquitin ligase ligand, is a selective bifunctional degrader of bromodomain-containing transcriptional regulator TRIM24 (transcriptional intermediary factor 1a). dTRIM24 induces rapid and sustain proteasome degradation of TRIM24 in 293FT cells.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
ligand: VL-269
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: −20°C
SMILES string: O=C(N1C)N(C)C2=C1C=C(OC3=CC=CC(OCCC)=C3)C(NS(C4=CC(C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N5C[C@H](O)C[C@H]5C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)=O)=O)=CC=C4)(=O)=O)=C2
ligand:
VL-269
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 2 mg/mL, clear
storage temp.:
−20°C
SMILES string:
O=C(N1C)N(C)C2=C1C=C(OC3=CC=CC(OCCC)=C3)C(NS(C4=CC(C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N5C[C@H](O)C[C@H]5C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)=O)=O)=CC=C4)(=O)=O)=C2
ligand: pomalidomide
Assay: ≥97% (HPLC)
form: powder
color: white to beige
solubility: H2O: 2 mg/mL, clear
storage temp.: −20°C
SMILES string: __
ligand:
pomalidomide
Assay:
≥97% (HPLC)
form:
powder
color:
white to beige
solubility:
H2O: 2 mg/mL, clear
storage temp.:
−20°C
SMILES string:
__
ligand: VH032
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: 2-8°C
SMILES string: __
ligand:
VH032
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 2 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
__
ligand: E7820
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: 2-8°C
SMILES string: __
ligand:
E7820
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 2 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
__