BDB564696
BD Pharmingen™ MitoStatus TMRE
Manufacturer: BD
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564696-Each-of-1 | In Stock | ₹ 16,153.73 |
BDB564696 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,153.73
GST (18%): ₹ 2,907.671
Total Price: ₹ 19,061.401
Quantity
25 mg
Storage Buffer
Lyophilized powder
Test Specificity
Tested in Development: Human, Mouse
Content And Storage
Upon arrival, store the dye powder desiccated and protected from light at ≤ -20°C until use. The dye powder is stable for at least 12 months if stored as indicated. After reconstitution with DMSO, store the stock solution at ≤ -20°C in small aliquots. The stock solution is stable for at least 6 months if stored as indicated.
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Description
- In cells undergoing apoptosis, pro-apoptotic Bcl-2 family proteins cause mitochondrial outer membrane permeabilization (MOMP), resulting in the release of cytochrome C and the subsequent activation of caspase-9 and the apoptotic cascade
- MOMP often correlates with the loss of inner mitochondrial membrane potential (ΔΨm), which can be detected using ΔΨm-sensitive dyes
- These cationic, lipophilic dyes accumulate within the mitochondria of healthy cells, but not within mitochondria that have lost ΔΨm due to induction of apoptosis or treatment with a mitochondrial uncoupler
- BD Pharmingen™ MitoStatus TMRE (Tetramethylrhodamine ethyl ester) is a fluorescent dye that is readily sequestered by active mitochondria, allowing for flow cytometric or imaging analysis to assess for apoptosis or mitochondrial depolarization
- Non-apoptotic or cells with polarized mitochondria will fluoresce red while apoptotic or cells with depolarizard mitochondria will have diminished levels of red fluorescence
- MitoStatus TMRE (Tetramethylrhodamine ethyl ester) has an excitation maximum of 549nm, but is well-excited by both the blue (e.g
- 488 nM) and yellow-green (e.g
- 561nM) lasers
- It has an emission maximum of 574nm.
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Quantity: 25 mg
Storage Buffer: Lyophilized powder
Test Specificity: Tested in Development: Human, Mouse
Content And Storage: Upon arrival, store the dye powder desiccated and protected from light at ≤ -20°C until use. The dye powder is stable for at least 12 months if stored as indicated. After reconstitution with DMSO, store the stock solution at ≤ -20°C in small aliquots. The stock solution is stable for at least 6 months if stored as indicated.
Quantity:
25 mg
Storage Buffer:
Lyophilized powder
Test Specificity:
Tested in Development: Human, Mouse
Content And Storage:
Upon arrival, store the dye powder desiccated and protected from light at ≤ -20°C until use. The dye powder is stable for at least 12 months if stored as indicated. After reconstitution with DMSO, store the stock solution at ≤ -20°C in small aliquots. The stock solution is stable for at least 6 months if stored as indicated.
Quantity: 100 μg
Storage Buffer: __
Test Specificity: Tested in Development: Human, Mouse
Content And Storage: Upon arrival, store the dye powder desiccated and protected from light at ≤ -20°C until use. The dye powder is stable for at least 12 months if stored as indicated. After reconstitution with DMSO, store the stock solution at ≤ -20°C in small aliquots. The stock solution is stable for at least 6 months if stored as indicated.
Quantity:
100 μg
Storage Buffer:
__
Test Specificity:
Tested in Development: Human, Mouse
Content And Storage:
Upon arrival, store the dye powder desiccated and protected from light at ≤ -20°C until use. The dye powder is stable for at least 12 months if stored as indicated. After reconstitution with DMSO, store the stock solution at ≤ -20°C in small aliquots. The stock solution is stable for at least 6 months if stored as indicated.
Quantity: 50 μg
Storage Buffer: __
Test Specificity: __
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Quantity:
50 μg
Storage Buffer:
__
Test Specificity:
__
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Quantity: 50 Tests
Storage Buffer: __
Test Specificity: __
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Quantity:
50 Tests
Storage Buffer:
__
Test Specificity:
__
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.