38-558-110MG

MilliporeSigma™ Calbiochem™ 11beta-HSD1 Inhibitor, 10j

Manufacturer: MilliporeSigma™

CAS Number: 1009373-58-3

Select a Size

Pack Size SKU Availability Price
Each of 1 38-558-110MG-Each-of-1 In Stock ₹ 23,921.72

38-558-110MG - Each of 1

₹ 23,921.72

In Stock

Quantity

1

Base Price: ₹ 23,921.72

GST (18%): ₹ 4,305.91

Total Price: ₹ 28,227.63

Color

White

CAS

1009373-58-3

Formula Weight

501.46g/mol

Form

Solid

Description

95% by HPLC

Molecular Formula

C26H33BrN2O3

Solubility

DMSO

Quantity

10 mg

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Description

  • A cell permeable, spirocyclic urea that acts as a selective inhibitor of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) (IC 50 of 1.6nM and 5.3 nM) in enzyme and human adipocyte assays, respectively
  • Consisting of 2 enantiomers, 10j2 (R Isomer) is shown to be ˜ 2-3X more potent than 10j1 (S Isomer), in both aforementioned assays
  • 11β-HSD1 activity in the presence of 10j2 (10mg/kg in animals p.o.) results in an ˜ 80% reduction in the concentration of plasma cortisol over vehicle treated controls.

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Img

MilliporeSigma™

38-558-110MG

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Color:
White

CAS:
1009373-58-3

Formula Weight:
501.46g/mol

Form:
Solid

Description:
95% by HPLC

Molecular Formula:
C26H33BrN2O3

Solubility:
DMSO

Quantity:
10 mg

Img

MilliporeSigma™

38-558-510MG

--


Color:
Yellow

CAS:
__

Formula Weight:
422.3g/mol

Form:
Solid

Description:
97% by HPLC

Molecular Formula:
C17H12BrNO3S2

Solubility:
DMSO

Quantity:
10 mg

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Invitrogen

38-580-0

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CAS:
__

Formula Weight:
__

Form:
Liquid

Description:
__

Molecular Formula:
__

Solubility:
__

Quantity:
100 μg

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Fischer Scientific

38-583-10

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Color:
__

CAS:
__

Formula Weight:
__

Form:
__

Description:
__

Molecular Formula:
__

Solubility:
__

Quantity:
__