40-009-150MG
MilliporeSigma™ Calbiochem™ HIF-Hydroxylase Inhibitor, DMOG
Manufacturer: MilliporeSigma™
CAS Number: 89464-63-1
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 40-009-150MG-Each-of-1 | In Stock | ₹ 9,811.36 |
40-009-150MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,811.36
GST (18%): ₹ 1,766.045
Total Price: ₹ 11,577.405
Color
White
CAS
89464-63-1
Formula Weight
175.1g/mol
Content And Storage
Hygroscopic
Quantity
50 mg
Description
98% by HPLC
Molecular Formula
C6H9NO5
Solubility
DMSO
Form
Solid
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-15893 100mg , DMOG CAS:89464-63-1 Purity:>98% | Medchemexpress LLC | ₹ 11,681.25 | |
 | Apexbio Technology LLC cell-permeable, competitive HIF-PH inhibitor 89464-63-1. MFCD05865098 | Apexbio Technology LLC | ₹ 5,340.00 | |
 | Sigma Aldrich Fine Chemicals Biosciences DMOG >=98% (HPLC) | 89464-63-1 | MFCD05865098 | 50MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 44,215.20 | |
 | Sigma Aldrich Fine Chemicals Biosciences DMOG | 89464-63-1 | MFCD05865098 | 10mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 11,230.02 | |
| | Cayman Chemical DMOG, 89464-63-1, 100 mg | Cayman Chemical | ₹ 14,124.30 | |
 | Cayman Chemical DMOG, 89464-63-1, 500 mg | Cayman Chemical | ₹ 59,839.15 | |
 | DMOG | ChemScene | ₹ 6,675.00 - ₹ 54,112.00 |
Related Products
Description
- A cell-permeable 2-OG (2-oxoglutarate) analog that is expected to act as a competitive inhibitor against all 2-OG-dependent dioxygenases
- Effectively upregulates normoxia HIF-α transcription activity (effective conc
- = 1mm in cultures) by inhibiting HIF-PH- (HIF-α-prolyl hydroxylase) catalyzed ODD (oxygen-dependent degradation domain) Prolyl hydroxylation (Pro 564 and Pro 530 in HIF-1α and HIF-2α, respectively) and aspartyl/asparanginyl β-hydroxylase-catalyzed CAD Asp hydroxylation (Asn 803 and Asn 851 in HIF-1α and HIF-2α, respectively), resulting in a blockage of pVHL (von Hippel-Lindau) ubiquitin ligase complex-mediated HIF-α degradation and a simultaneous promotion of HIF CAD (COOH-terminal activation domain) p300/CBP association
- DMOG is also demonstrated to augment artery ligation-induced up-regulation of HIF-1α and FLK (by 100% and 40%, respectively, in 11 days; 8mg/0.5 ml/animal/i.p.; q.o.d.) in muscle tissues in a murine ischaemic model in vivo .
Compare Similar Items
Show Difference
Color: White
CAS: 89464-63-1
Formula Weight: 175.1g/mol
Content And Storage: Hygroscopic
Quantity: 50 mg
Description: 98% by HPLC
Molecular Formula: C6H9NO5
Solubility: DMSO
Form: Solid
Color:
White
CAS:
89464-63-1
Formula Weight:
175.1g/mol
Content And Storage:
Hygroscopic
Quantity:
50 mg
Description:
98% by HPLC
Molecular Formula:
C6H9NO5
Solubility:
DMSO
Form:
Solid
Color: __
CAS: 934593-90-5
Formula Weight: 435.5g/mol
Content And Storage: Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light
Quantity: 5 mg
Description: 95% by HPLC
Molecular Formula: C26H29NO5
Solubility: __
Form: Liquid
Color:
__
CAS:
934593-90-5
Formula Weight:
435.5g/mol
Content And Storage:
Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light
Quantity:
5 mg
Description:
95% by HPLC
Molecular Formula:
C26H29NO5
Solubility:
__
Form:
Liquid
Color: White
CAS: __
Formula Weight: 346.7g/mol
Content And Storage: Protect from light
Quantity: 10 mg
Description: 99% by HPLC
Molecular Formula: C12H6ClF3N4O3
Solubility: DMSO
Form: Solid
Color:
White
CAS:
__
Formula Weight:
346.7g/mol
Content And Storage:
Protect from light
Quantity:
10 mg
Description:
99% by HPLC
Molecular Formula:
C12H6ClF3N4O3
Solubility:
DMSO
Form:
Solid
Color: __
CAS: __
Formula Weight: __
Content And Storage: −20°C
Quantity: 500 μg
Description: __
Molecular Formula: __
Solubility: __
Form: Liquid
Color:
__
CAS:
__
Formula Weight:
__
Content And Storage:
−20°C
Quantity:
500 μg
Description:
__
Molecular Formula:
__
Solubility:
__
Form:
Liquid