42-020-510MG
MilliporeSigma™ Calbiochem™ Histone Lysine Demethylase Inhibitor VIII, GSK-J4
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 42-020-510MG-Each-of-1 | In Stock | ₹ 23,709.60 |
42-020-510MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,709.60
GST (18%): ₹ 4,267.728
Total Price: ₹ 27,977.328
Color
Tan
Target Proteins
H3K27me3 demethylases JMJD3 & UTX
Formula Weight
417.5g/mol
Content And Storage
Protect from light
Quantity
10 mg
Description
98% by HPLC
Molecular Formula
C24H27N5O2
Solubility
DMSO
Form
Semi-solid
Related Products
Description
- A cell-permeable GSK-J1 (Cat
- No
- 420204) prodrug that is ineffective in cell-free assays, but is effectively converted to GSK-J1 intracellularly for effective JMJD3 and UTX inhibition (effective conc
- 25 to 50μM in HeLa cultures)
- GSK-J4 treatment is shown to block LPS-induced TNF-α production in primary human macrophage cultures (IC 50 = 9μM by ELISA)
- This probe is supplied in conjunction with the Structural Genomics Consortium (SGC)
- For further characterization details, please visit the SGC website (http://www.thesgc.org/scientists/chemical_probes/GSKJ1).
Compare Similar Items
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Color: Tan
Target Proteins: H3K27me3 demethylases JMJD3 & UTX
Formula Weight: 417.5g/mol
Content And Storage: Protect from light
Quantity: 10 mg
Description: 98% by HPLC
Molecular Formula: C24H27N5O2
Solubility: DMSO
Form: Semi-solid
Color:
Tan
Target Proteins:
H3K27me3 demethylases JMJD3 & UTX
Formula Weight:
417.5g/mol
Content And Storage:
Protect from light
Quantity:
10 mg
Description:
98% by HPLC
Molecular Formula:
C24H27N5O2
Solubility:
DMSO
Form:
Semi-solid
Color: Off-white
Target Proteins: Induces cyclopia by blocking shh (Sonic Hedgehog) signaling
Formula Weight: 425.6g/mol
Content And Storage: __
Quantity: 1 mg
Description: 98% by HPLC; single spot by TLC
Molecular Formula: C27H39NO3
Solubility: DMSO or EtOH
Form: Solid
Color:
Off-white
Target Proteins:
Induces cyclopia by blocking shh (Sonic Hedgehog) signaling
Formula Weight:
425.6g/mol
Content And Storage:
__
Quantity:
1 mg
Description:
98% by HPLC; single spot by TLC
Molecular Formula:
C27H39NO3
Solubility:
DMSO or EtOH
Form:
Solid
Color: Tan
Target Proteins: __
Formula Weight: 311.4g/mol
Content And Storage: Protect from light
Quantity: 10 mg
Description: 98% by HPLC
Molecular Formula: C15H13N5OS
Solubility: DMSO
Form: Powder
Color:
Tan
Target Proteins:
__
Formula Weight:
311.4g/mol
Content And Storage:
Protect from light
Quantity:
10 mg
Description:
98% by HPLC
Molecular Formula:
C15H13N5OS
Solubility:
DMSO
Form:
Powder
Color: Brown
Target Proteins: __
Formula Weight: 304.39g/mol
Content And Storage: __
Quantity: 10 mg
Description: 95% by HPLC
Molecular Formula: C19H20N4
Solubility: DMSO
Form: Solid
Color:
Brown
Target Proteins:
__
Formula Weight:
304.39g/mol
Content And Storage:
__
Quantity:
10 mg
Description:
95% by HPLC
Molecular Formula:
C19H20N4
Solubility:
DMSO
Form:
Solid