48-002-65MG
MilliporeSigma™ Calbiochem™ NBD-Binding Peptide II, Cell Permeable, CTP-NBD
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 48-002-65MG-Each-of-1 | In Stock | ₹ 33,813.31 |
48-002-65MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,813.31
GST (18%): ₹ 6,086.396
Total Price: ₹ 39,899.706
Color
White
Description
97% by HPLC
Formula Weight
2846.2g/mol
Content And Storage
Hygroscopic, Protect from light
Quantity
5 mg
Formulation
Supplied as a trifluoroacetate salt.
Target Proteins
NEMO-binding peptide
Solubility
H2O
Form
Solid
Related Products
Description
- A cell-permeable cytoplasmic transduction peptide (CTP; YGRRARRRARR) fused to the NEMO binding domain peptide (NBD; TALDWSWLQTE) that acts as a potent inhibitor of TNFα-stimulated NF-κB activity (IC 50 ∽ 50μM in HCT116 cells)
- Acts by interfering with the formation of active IKK complex and thereby prevents IκBα phosphorylation and its subsequent proteasomal degradation
- Also blocks LPS-mediated increase in inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) activities
- Colon-targeted capsules containing CTP-NBD are shown to reduce 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in rodent models (4.5mg/kg/,p.o.) in vivo and diminish activities of myeloperoxidase and several inflammatory mediators
- Antennapedia fused NBD cell-permeable peptide is also available ( Cat
- No
- 480025).
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Color: White
Description: 97% by HPLC
Formula Weight: 2846.2g/mol
Content And Storage: Hygroscopic, Protect from light
Quantity: 5 mg
Formulation: Supplied as a trifluoroacetate salt.
Target Proteins: NEMO-binding peptide
Solubility: H2O
Form: Solid
Color:
White
Description:
97% by HPLC
Formula Weight:
2846.2g/mol
Content And Storage:
Hygroscopic, Protect from light
Quantity:
5 mg
Formulation:
Supplied as a trifluoroacetate salt.
Target Proteins:
NEMO-binding peptide
Solubility:
H2O
Form:
Solid
Color: __
Description: __
Formula Weight: __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Quantity: 100 μL
Formulation: 10mM HEPES buffered saline with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Target Proteins: __
Solubility: __
Form: Liquid
Color:
__
Description:
__
Formula Weight:
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Quantity:
100 μL
Formulation:
10mM HEPES buffered saline with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Target Proteins:
__
Solubility:
__
Form:
Liquid
Color: __
Description: __
Formula Weight: __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Quantity: 100 Tests
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Target Proteins: __
Solubility: __
Form: Liquid
Color:
__
Description:
__
Formula Weight:
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Quantity:
100 Tests
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Target Proteins:
__
Solubility:
__
Form:
Liquid
Color: __
Description: __
Formula Weight: __
Content And Storage: Store the unopened product at room temperature
Quantity: 50 mL
Formulation: __
Target Proteins: __
Solubility: __
Form: __
Color:
__
Description:
__
Formula Weight:
__
Content And Storage:
Store the unopened product at room temperature
Quantity:
50 mL
Formulation:
__
Target Proteins:
__
Solubility:
__
Form:
__