50-052-70001
MilliporeSigma™ Calbiochem™ APETx2, Anthopleura elegantissima, Recombinant,E.coli
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-052-70001-Each-of-1 | In Stock | ₹ 41,474.00 |
50-052-70001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,474.00
GST (18%): ₹ 7,465.32
Total Price: ₹ 48,939.32
Formulation
Supplied as a trifluoroacetate salt.
Target Proteins
ASIC3
Formula Weight
4561g/mol
Content And Storage
Protect from light
Quantity
100 μg
Description
95% by HPLC
Molecular Formula
C196H280N54O61S6
Solubility
Aqueous buffer
Form
Lyophilized
Related Products
Description
- Originally isolated from sea anemone Anthopleura elegantissima , the 42 amino-acid toxin APETx2 is shown to block acidification-induced activation of homotrimeric acid-sensing ion channel composed of rat or human ASIC3, but not rat ASIC1a, ASIC1b, or ASIC2a, in a reversible manner
- APETx2 is also shown to inhibit the Na + -dependent, alkalization-induced nonconventional channel activity seen in human, but not rat, ASIC3
- APETx2 in vivo efficacy is demonstrated in various rat pain induction models (100μL 2.2μM APETx2 via i.m
- injection)
- Reported to display much reduced potency against Kv3.4 and little or no effect toward hERG, Kv2.2, Kv3.1, Kv4.2, or Kv4.3 channel activity.
Compare Similar Items
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Formulation: Supplied as a trifluoroacetate salt.
Target Proteins: ASIC3
Formula Weight: 4561g/mol
Content And Storage: Protect from light
Quantity: 100 μg
Description: 95% by HPLC
Molecular Formula: C196H280N54O61S6
Solubility: Aqueous buffer
Form: Lyophilized
Formulation:
Supplied as a trifluoroacetate salt.
Target Proteins:
ASIC3
Formula Weight:
4561g/mol
Content And Storage:
Protect from light
Quantity:
100 μg
Description:
95% by HPLC
Molecular Formula:
C196H280N54O61S6
Solubility:
Aqueous buffer
Form:
Lyophilized
Formulation: __
Target Proteins: Major hubs involved in TLR signaling cascade
Formula Weight: __
Content And Storage: Hygroscopic, Protect from light
Quantity: 1 Each
Description: __
Molecular Formula: __
Solubility: __
Form: Solid
Formulation:
__
Target Proteins:
Major hubs involved in TLR signaling cascade
Formula Weight:
__
Content And Storage:
Hygroscopic, Protect from light
Quantity:
1 Each
Description:
__
Molecular Formula:
__
Solubility:
__
Form:
Solid
Formulation: __
Target Proteins: __
Formula Weight: __
Content And Storage: __
Quantity: __
Description: __
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Target Proteins:
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Formulation: __
Target Proteins: __
Formula Weight: __
Content And Storage: __
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Description: __
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Target Proteins:
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