50-576-70001

MilliporeSigma™ Calbiochem™ GSK-3beta Inhibitor XXVII, CESI

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 50-576-70001-Each-of-1 In Stock ₹ 23,479.38

50-576-70001 - Each of 1

₹ 23,479.38

In Stock

Quantity

1

Base Price: ₹ 23,479.38

GST (18%): ₹ 4,226.288

Total Price: ₹ 27,705.668

Color

Yellow

Target Proteins

GSK3b

Solubility

DMSO

Form

Solid

Description

96% by HPLC

Molecular Formula

C19H16ClNO6S

Content And Storage

Protect from light

Quantity

10 mg

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Description

  • A cell-permeable, 3-hydroxychromone derived compound that acts as a selective and reversible inhibitor of GSK-3β (IC 50 < 100nM)
  • Shown to increase phosphorylation at Ser9
  • Does not show any inhibitory effect on a panel of 15 other protein kinases, including AMPK and Akt
  • By blocking GSK-3β activity, it acts as a positive regulator of b-catenin signaling
  • Does not affect the viability or the growth rate of 3T3-L1 preadipocytes, however, it significantly reduces their differentiation into adipocytes (˜ 50 to 100nM)
  • Exerts anti-adipogenic activity by down-regulating C/EBPa and PPARg
  • Shown to reduce adipocyte size and diminish weight gain in diet-induced obese mice without affecting their daily food intake.

Compare Similar Items

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Img

MilliporeSigma™

50-576-70001

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Color:
Yellow

Target Proteins:
GSK3b

Solubility:
DMSO

Form:
Solid

Description:
96% by HPLC

Molecular Formula:
C19H16ClNO6S

Content And Storage:
Protect from light

Quantity:
10 mg

Img

MilliporeSigma™

50-577-10001

--


Color:
White

Target Proteins:
Muscarinic Receptors

Solubility:
DMSO or EtOH

Form:
Solid

Description:
99% by HPLC

Molecular Formula:
C21H26INO2

Content And Storage:
Protect from light

Quantity:
25 mg

Img

MilliporeSigma™

50-577-20001

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Color:
White

Target Proteins:
M1

Solubility:
H2O

Form:
Solid

Description:
99% by HPLC

Molecular Formula:
C19H21N5O2·2HCl

Content And Storage:
Protect from light

Quantity:
100 mg

Img

Invitrogen

50-578-982

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Color:
__

Target Proteins:
__

Solubility:
__

Form:
Liquid

Description:
__

Molecular Formula:
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Quantity:
100 μg