MilliporeSigma™ Calbiochem™ (R)-(+)-SKF38393 Hydrochloride

Description

• A benzazepine derivative that acts as a selective Dopamine D 1 /D 5 receptor partial agonist
• Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer
• The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity
• Reported to have stimulant and anorectic effects.