50-598-00001

MilliporeSigma™ Calbiochem™ Autophagy Inhibitor IV, Cpd18

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 50-598-00001-Each-of-1 In Stock ₹ 11,740.54

50-598-00001 - Each of 1

₹ 11,740.54

In Stock

Quantity

1

Base Price: ₹ 11,740.54

GST (18%): ₹ 2,113.297

Total Price: ₹ 13,853.837

Color

White

Target Proteins

PI3K

Solubility

DMSO

Form

Solid

Description

98% by HPLC

Molecular Formula

C12H17N5

Content And Storage

Protect from light

Quantity

10 mg

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Description

  • A cell-permeable 3-methyladenine (3-MA) derivative that acts as an autophagy inhibitor via the inhibition of class III PI3K, and without touching class I PI3K
  • Shown to block 80% of starvation-induced autophagy at 1mm (IC 50 = 0.67 mM, compared with 3-MA at 6 mM)
  • Displays much better solubility than 3-MA (5 times more soluble in water and 30 times more soluble in DMSO)
  • Also found to reduce cell viability by 55% at 1mm at 12 hours compared with 72% reduction for 3-MA at 10 mM
  • Please note that the molecular weight for this compound is lot-specific due to variable water content.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

50-598-00001

--


Color:
White

Target Proteins:
PI3K

Solubility:
DMSO

Form:
Solid

Description:
98% by HPLC

Molecular Formula:
C12H17N5

Content And Storage:
Protect from light

Quantity:
10 mg

Img

MilliporeSigma™

50-598-10001

--


Color:
White

Target Proteins:
peripheral bezodiazepine receptor

Solubility:
DMSO

Form:
Solid

Description:
98% by HPLC

Molecular Formula:
C21H21ClN2O

Content And Storage:
Protect from light

Quantity:
10 mg

Img

MilliporeSigma™

50-598-30001

--


Color:
Beige

Target Proteins:
α7 AChR

Solubility:
DMSO

Form:
Powder

Description:
99% by HPLC

Molecular Formula:
C14H9Cl2F3N2O2

Content And Storage:
Protect from light

Quantity:
10 mg

Img

MilliporeSigma™

50-598-40001

--


Color:
Off-white

Target Proteins:
__

Solubility:
DMSO

Form:
Powder

Description:
98% by HPLC

Molecular Formula:
C25H21N3O2S2

Content And Storage:
Protect from light

Quantity:
25 mg