50-598-10001

MilliporeSigma™ Calbiochem™ PK11195

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 50-598-10001-Each-of-1 In Stock ₹ 9,683.68

50-598-10001 - Each of 1

₹ 9,683.68

In Stock

Quantity

1

Base Price: ₹ 9,683.68

GST (18%): ₹ 1,743.062

Total Price: ₹ 11,426.742

Color

White

Target Proteins

peripheral bezodiazepine receptor

Solubility

DMSO

Form

Solid

Description

98% by HPLC

Molecular Formula

C21H21ClN2O

Content And Storage

Protect from light

Quantity

10 mg

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Description

  • An isoquinoline carboxamide that acts as a potent ligand for peripheral bezodiazepine receptor (K d = 20nM)
  • Exhibits anti-inflammatory properties
  • Binds to monocytes and following lesioning its binding up-regulated in brain macrophages and activated microglia
  • Shown to enhance the susceptibility of cells to apoptosis induction by DNA damaging agents and can reverse the suppression of apoptosis by Bcl-2
  • Serves as a ligand of the outer membrane translocator protein and reduces mitochondrial transmembrane potential within 30 minutes of exposure (˜100μM).

Compare Similar Items

Show Difference

Img

MilliporeSigma™

50-598-10001

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Color:
White

Target Proteins:
peripheral bezodiazepine receptor

Solubility:
DMSO

Form:
Solid

Description:
98% by HPLC

Molecular Formula:
C21H21ClN2O

Content And Storage:
Protect from light

Quantity:
10 mg

Img

MilliporeSigma™

50-598-30001

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Color:
Beige

Target Proteins:
α7 AChR

Solubility:
DMSO

Form:
Powder

Description:
99% by HPLC

Molecular Formula:
C14H9Cl2F3N2O2

Content And Storage:
Protect from light

Quantity:
10 mg

Img

MilliporeSigma™

50-598-40001

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Color:
Off-white

Target Proteins:
__

Solubility:
DMSO

Form:
Powder

Description:
98% by HPLC

Molecular Formula:
C25H21N3O2S2

Content And Storage:
Protect from light

Quantity:
25 mg

Img

MilliporeSigma™

50-598-50001

--


Color:
Light Yellow

Target Proteins:
CFTR

Solubility:
DMSO

Form:
Powder

Description:
98% by HPLC

Molecular Formula:
C16H13N5O

Content And Storage:
Protect from light

Quantity:
10 mg