50-617-310MG
MilliporeSigma™ Calbiochem™ p38 MAP Kinase Inhibitor XI
Manufacturer: MilliporeSigma™
The price for this product is unavailable. Please request a quote
Color
Light Beige
Molecular Formula
C21H14F2N2O
Solubility
DMSO
Form
Powder
Description
98% by HPLC
Formula Weight
348.4g/mol
Content And Storage
Hygroscopic, Protect from light
Quantity
10 mg
Related Products
Description
- A cell-permeable naphthyridine N-oxide compound that acts as a potent, reversible p38α MAP kinase inhibitor (IC 50 = 68nM) and exhibits excellent selectivity among 54-kinases
- It acts on the ATP-binding site plus an adjacent hydrophobic pocket
- Exhibits desirable ADME (Absorption, Distribution, Metabolism, and Excretion) profile with good microsomal stability, low toxicity, and low reactivity towards cytochrome P450 isozymes
- Shown to inhibit lipopolysaccharide-induced TNFα production in a dose-dependent manner (ED 50 of 0.5mg/kg).
Compare Similar Items
Show Difference
Color: Light Beige
Molecular Formula: C21H14F2N2O
Solubility: DMSO
Form: Powder
Description: 98% by HPLC
Formula Weight: 348.4g/mol
Content And Storage: Hygroscopic, Protect from light
Quantity: 10 mg
Color:
Light Beige
Molecular Formula:
C21H14F2N2O
Solubility:
DMSO
Form:
Powder
Description:
98% by HPLC
Formula Weight:
348.4g/mol
Content And Storage:
Hygroscopic, Protect from light
Quantity:
10 mg
Color: __
Molecular Formula: __
Solubility: __
Form: __
Description: __
Formula Weight: __
Content And Storage: __
Quantity: __
Color:
__
Molecular Formula:
__
Solubility:
__
Form:
__
Description:
__
Formula Weight:
__
Content And Storage:
__
Quantity:
__
Color: __
Molecular Formula: C150H227N57O32S2
Solubility: DMSO
Form: Lyophilized
Description: 95% by HPLC
Formula Weight: 3404.9g/mol
Content And Storage: Hygroscopic, Protect from light
Quantity: 500 μg
Color:
__
Molecular Formula:
C150H227N57O32S2
Solubility:
DMSO
Form:
Lyophilized
Description:
95% by HPLC
Formula Weight:
3404.9g/mol
Content And Storage:
Hygroscopic, Protect from light
Quantity:
500 μg
Color: __
Molecular Formula: __
Solubility: __
Form: __
Description: __
Formula Weight: __
Content And Storage: __
Quantity: __
Color:
__
Molecular Formula:
__
Solubility:
__
Form:
__
Description:
__
Formula Weight:
__
Content And Storage:
__
Quantity:
__