53-962-0250NG
MilliporeSigma™ Calbiochem™ PP2A Inhibitor II, GST-Fusion, Human, Recombinant,E.coli
Manufacturer: MilliporeSigma™
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Formulation
In 50 mM Tris-HCl, 14 mM βME, 1 mM benzamidine, 1 mM EDTA, 0.1 mM PMSF, 10% glycerol, pH 7.4.
Target Proteins
PP2A
Content And Storage
Avoid Freeze-Thaw Cycles
Quantity
250 NG
Description
90% by SDS-PAGE
Formula Weight
67000g/mol
Form
Liquid
Related Products
Description
- Recombinant, human PP2AI I 2 fused to GST and expressed in E
- coli
- Inhibits protein phosphatase 2A (PP2A) potently with K i ∽ 25-30nM with myelin basic protein, histone H1, and other substrates of PP2A but not with casein as a substrate
- Stimulates PP1
- Prevents inhibition of E-Cdk-2 by p21 Cip1
- Associates with B cyclin
- Regulates histone binding to DNA, transcriptional activity and chromatin condensation
- Undergoes phosphorylation in cells
- Highly expressed in some cancers
- Associates with HRX leukemia-associated fusion proteins
- Occurs as fusion protein in acute undifferentiated leukemia
- Does not inhibit PP1, PP2B, PP2C, or pyruvate dehydrogenase.
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Formulation: In 50 mM Tris-HCl, 14 mM βME, 1 mM benzamidine, 1 mM EDTA, 0.1 mM PMSF, 10% glycerol, pH 7.4.
Target Proteins: PP2A
Content And Storage: Avoid Freeze-Thaw Cycles
Quantity: 250 NG
Description: 90% by SDS-PAGE
Formula Weight: 67000g/mol
Form: Liquid
Formulation:
In 50 mM Tris-HCl, 14 mM βME, 1 mM benzamidine, 1 mM EDTA, 0.1 mM PMSF, 10% glycerol, pH 7.4.
Target Proteins:
PP2A
Content And Storage:
Avoid Freeze-Thaw Cycles
Quantity:
250 NG
Description:
90% by SDS-PAGE
Formula Weight:
67000g/mol
Form:
Liquid
Formulation: Supplied as a trifluoroacetate salt.
Target Proteins: insulin-stimulated transport in intact adinocytes
Content And Storage: Hygroscopic
Quantity: 500 μg
Description: 97% by HPLC
Formula Weight: 1928.4g/mol
Form: Lyophilized
Formulation:
Supplied as a trifluoroacetate salt.
Target Proteins:
insulin-stimulated transport in intact adinocytes
Content And Storage:
Hygroscopic
Quantity:
500 μg
Description:
97% by HPLC
Formula Weight:
1928.4g/mol
Form:
Lyophilized
Formulation: Supplied as a trifluoroacetate salt.
Target Proteins: protein kinase Cθ
Content And Storage: Hygroscopic
Quantity: 500 μg
Description: 95% by HPLC
Formula Weight: 2318.9g/mol
Form: Lyophilized
Formulation:
Supplied as a trifluoroacetate salt.
Target Proteins:
protein kinase Cθ
Content And Storage:
Hygroscopic
Quantity:
500 μg
Description:
95% by HPLC
Formula Weight:
2318.9g/mol
Form:
Lyophilized
Formulation: __
Target Proteins: PKCα, PKCβ, PKCγ, PKCδ PKCε, Chk1, Cdc25C-associated protein kinase 1, Cdk1, PAK4, Cdk5/p25 and Chk2, PDK1, lck, MAPKAP kinase-2, Akt, GSK-3β and PKA
Content And Storage: Protect from light
Quantity: 500 μg
Description: 95% by HPLC
Formula Weight: 482.5g/mol
Form: Solid
Formulation:
__
Target Proteins:
PKCα, PKCβ, PKCγ, PKCδ PKCε, Chk1, Cdc25C-associated protein kinase 1, Cdk1, PAK4, Cdk5/p25 and Chk2, PDK1, lck, MAPKAP kinase-2, Akt, GSK-3β and PKA
Content And Storage:
Protect from light
Quantity:
500 μg
Description:
95% by HPLC
Formula Weight:
482.5g/mol
Form:
Solid