65-427-010MG

MilliporeSigma™ Calbiochem™ TNP-470

Manufacturer: MilliporeSigma™

CAS Number: 129298-91-5

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Color

White to Light Yellow

CAS

129298-91-5

Formula Weight

401.9g/mol

Form

Solid

Description

97% by HPLC

Molecular Formula

C19H28CINO6

Solubility

DMSO

Quantity

10 mg

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Description

  • A cell-permeable Fumagillin (Cat
  • No
  • 344845) analog that inhibits MetAP2, but not MetAP1, methionine aminopeptidase activity (IC 50 = 1nM against human MetAP2), without affecting the inhibitory activity of MetAP2 against HRI- (heme-regulated inhibitor kinase) catalyzed eIF-2α phosphorylation
  • A potent endothelial cytostasis inducer (IC 50 = 25 pM and 37 pM, respectively, against HUVEC and bovine BAEC) in vitro and an effective anti-angiogenesis agent in vivo (2 to 100mg/kg in mice and rats; s.c.).

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MilliporeSigma™

65-427-010MG

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Color:
White to Light Yellow

CAS:
129298-91-5

Formula Weight:
401.9g/mol

Form:
Solid

Description:
97% by HPLC

Molecular Formula:
C19H28CINO6

Solubility:
DMSO

Quantity:
10 mg

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Fischer Scientific

65-481-0

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Color:
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CAS:
168982-69-2

Formula Weight:
297.39

Form:
__

Description:
__

Molecular Formula:
C16H27NO4

Solubility:
__

Quantity:
10 mg

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Fischer Scientific

65-485-0

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Color:
__

CAS:
168982-69-2

Formula Weight:
297.39

Form:
__

Description:
__

Molecular Formula:
C16H27NO4

Solubility:
__

Quantity:
50 mg

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Fischer Scientific

65-501

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Color:
__

CAS:
__

Formula Weight:
__

Form:
__

Description:
__

Molecular Formula:
__

Solubility:
__

Quantity:
2 mL