7060086
MilliporeSigma™ Calbiochem™ G-Protein βγ Binding Peptide, mSIRK
A cell-permeable, N-myristoylated G-protein βγ selective binding peptide that disrupts the interaction between α and βγ subunits and promotes the α subunit dissociation without stimulating nucleotide exchange.
Manufacturer: Fischer Scientific
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Formulation
Supplied as a trifluoroacetate salt.
Target Proteins
N-myristoylated G-protein βγ selective binding
Formula Weight
1948.3g/mol
Content And Storage
Hygroscopic
Description
95% by HPLC
Molecular Formula
C93H150N20O25
Solubility
DMSO
Form
Lyophilized
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Description
- A cell-permeable, N-myristoylated G-protein βγ selective binding peptide that disrupts the interaction between α and βγ subunits and promotes the α subunit dissociation without stimulating nucleotide exchange
- Shown to cause a rapid activation of ERK1/2 (EC 50 ∽ 2.5 - 5μM) in rat arterial smooth muscle and Rat2 cells
- Also promotes the phosphorylation of JNK and p38 MAP kinase, phospholipase C and causes Ca 2+ release from internal stores
- Negative control is also available (Cat
- No
- 371820).
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Formulation: Supplied as a trifluoroacetate salt.
Target Proteins: N-myristoylated G-protein βγ selective binding
Formula Weight: 1948.3g/mol
Content And Storage: Hygroscopic
Description: 95% by HPLC
Molecular Formula: C93H150N20O25
Solubility: DMSO
Form: Lyophilized
Formulation:
Supplied as a trifluoroacetate salt.
Target Proteins:
N-myristoylated G-protein βγ selective binding
Formula Weight:
1948.3g/mol
Content And Storage:
Hygroscopic
Description:
95% by HPLC
Molecular Formula:
C93H150N20O25
Solubility:
DMSO
Form:
Lyophilized
Formulation: __
Target Proteins: caspase-1, human recombinant
Formula Weight: 492.5g/mol
Content And Storage: Protect from light
Description: 97% by HPLC
Molecular Formula: C23H32N4O8
Solubility: DMSO or H2O
Form: Powder
Formulation:
__
Target Proteins:
caspase-1, human recombinant
Formula Weight:
492.5g/mol
Content And Storage:
Protect from light
Description:
97% by HPLC
Molecular Formula:
C23H32N4O8
Solubility:
DMSO or H2O
Form:
Powder
Formulation: __
Target Proteins: TIR domain-mediated MyD88/IL1-RI interaction
Formula Weight: 302.4g/mol
Content And Storage: __
Description: 95% by HPLC
Molecular Formula: C18H26N2O2
Solubility: DMSO or EtOH
Form: Oil
Formulation:
__
Target Proteins:
TIR domain-mediated MyD88/IL1-RI interaction
Formula Weight:
302.4g/mol
Content And Storage:
__
Description:
95% by HPLC
Molecular Formula:
C18H26N2O2
Solubility:
DMSO or EtOH
Form:
Oil
Formulation: __
Target Proteins: murine JAK1
Formula Weight: 309.3g/mol
Content And Storage: Protect from light
Description: 98% by HPLC
Molecular Formula: C18H16FN3O
Solubility: DMSO
Form: Solid
Formulation:
__
Target Proteins:
murine JAK1
Formula Weight:
309.3g/mol
Content And Storage:
Protect from light
Description:
98% by HPLC
Molecular Formula:
C18H16FN3O
Solubility:
DMSO
Form:
Solid