7112412

Tocris Bioscience™ NAV 2729

Selective ARF6 inhibitor

Manufacturer: Fischer Scientific

CAS Number: 419547-11-8

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Color

Yellow

CAS

419547-11-8

Formula Weight

456.88g/mol

Content And Storage

Store at 4°C

Product Type

Inhibitor

Molecular Formula

C25H17ClN4O3

Solubility

Soluble to 100mM in DMSO

For Use With (Application)

Blocks downstream signaling pathways

Other Options

Image Product Name Manufacturer Price Range
59-861-0
Tocris Bioscience™ NAV 2729
Fischer Scientific ₹ 25,069.08
59-865-0
Tocris Bioscience™ NAV 2729
Fischer Scientific ₹ 1,04,468.76
50-226-0552
Medchemexpress LLC HY-112473 10mg , NAV-2729 CAS:419547-11-8 Purity:>98%
Medchemexpress LLC ₹ 11,858.62
50-175-5572
Sigma Aldrich Fine Chemicals Biosciences NAV-2729 >=98% (HPLC) | 419547-11-8 | MFCD01455625 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 11,005.58
AX63124
419547-11-8 | 3-(4-Chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
A2B Chem ₹ 2,481.24 - ₹ 25,924.68

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Description

  • Selective ARF6 inhibitor (IC50 = 1.0 μM)
  • Selective for ARF6 over other ARF family members and small GTPases
  • Inhibits ARF6 activation in uveal melanoma cells in vitro and blocks downstream signaling pathways of oncogenic GNAQ
  • Reduces tumorigenesis in mouse model of uveal melanoma.

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Selective ARF6 inhibitor...


Color:
Yellow

CAS:
419547-11-8

Formula Weight:
456.88g/mol

Content And Storage:
Store at 4°C

Product Type:
Inhibitor

Molecular Formula:
C25H17ClN4O3

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Soluble to 100mM in DMSO

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