PHR1388
Adapalene
Pharmaceutical Secondary Standard; Certified Reference Material
Manufacturer: Supelco
CAS Number: 106685-40-9
Synonym(S): Adapalene, 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid, 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid, CD-271, Differin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 500 MG | PHR1388-500-MG | In Stock | ₹ 13,000.83 |
PHR1388 - 500 MG
In Stock
Quantity
1
Base Price: ₹ 13,000.83
GST (18%): ₹ 2,340.149
Total Price: ₹ 15,340.979
grade
certified reference materialpharmaceutical secondary standard
Quality Level
300
Agency
traceable to Ph. Eur. Y0001121traceable to USP 1011709
API family
adapalene
CofA
current certificate can be downloaded
technique(s)
HPLC: suitablegas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
COc1ccc(cc1C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)-c5ccc6cc(ccc6c5)C(O)=O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Adapalene | Sigma Aldrich | ₹ 16,107.60 | |
| | Adapalene for peak identification | Sigma Aldrich | ₹ 14,267.35 | |
| | Adapalene | Sigma Aldrich | ₹ 23,944.90 |
Description
- General description: Adapalene is a third-generation synthetic retinoid and a highly lipophilic compound derived from naphthoic acid. It is widely used in the treatment of acne.[1]
- Application: Adapalene may be used as a pharmaceutical reference standard for the quantification of the analyte in topical gel formulations using high-performance liquid chromatography technique.[1][2]
- Biochem/physiol Actions: Retinoic acid analogue that is a RARβ and RARγ agonist (AC50 values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RARγ, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cells in vitro. Displays comedolytic activity. Its unique pharmacological properties make it superior to other retinoids for the treatment of acne.
- Analysis Note: These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
- Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
- Footnote: To see an example of a Certificate of Analysis for this material enter LRAC3530 in the slot below. This is an example certificate only and may not be the lot that you receive.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
grade: certified reference materialpharmaceutical secondary standard
Quality Level: 300
Agency: traceable to Ph. Eur. Y0001121traceable to USP 1011709
API family: adapalene
CofA: current certificate can be downloaded
technique(s): HPLC: suitablegas chromatography (GC): suitable
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-30°C
SMILES string: COc1ccc(cc1C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)-c5ccc6cc(ccc6c5)C(O)=O
grade:
certified reference materialpharmaceutical secondary standard
Quality Level:
300
Agency:
traceable to Ph. Eur. Y0001121traceable to USP 1011709
API family:
adapalene
CofA:
current certificate can be downloaded
technique(s):
HPLC: suitablegas chromatography (GC): suitable
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-30°C
SMILES string:
COc1ccc(cc1C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)-c5ccc6cc(ccc6c5)C(O)=O
grade: certified reference materialpharmaceutical secondary standard
Quality Level: 300
Agency: traceable to Ph. Eur. P3750000
API family: propyphenazone
CofA: current certificate can be downloaded
technique(s): HPLC: suitablegas chromatography (GC): suitable
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: O=C1C(C(C)C)=C(C)N(C)N1C2=CC=CC=C2
grade:
certified reference materialpharmaceutical secondary standard
Quality Level:
300
Agency:
traceable to Ph. Eur. P3750000
API family:
propyphenazone
CofA:
current certificate can be downloaded
technique(s):
HPLC: suitablegas chromatography (GC): suitable
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
O=C1C(C(C)C)=C(C)N(C)N1C2=CC=CC=C2
grade: certified reference materialpharmaceutical secondary standard
Quality Level: 300
Agency: traceable to BP 872traceable to Ph. Eur. Y0000773traceable to USP 1356916
API family: lansoprazole
CofA: current certificate can be downloaded
technique(s): HPLC: suitablegas chromatography (GC): suitable
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F
grade:
certified reference materialpharmaceutical secondary standard
Quality Level:
300
Agency:
traceable to BP 872traceable to Ph. Eur. Y0000773traceable to USP 1356916
API family:
lansoprazole
CofA:
current certificate can be downloaded
technique(s):
HPLC: suitablegas chromatography (GC): suitable
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F
grade: certified reference materialpharmaceutical secondary standard
Quality Level: 300
Agency: traceable to Ph. Eur. P2670000traceable to USP 1554603
API family: praziquantel
CofA: current certificate can be downloaded
technique(s): HPLC: suitablegas chromatography (GC): suitable
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4
grade:
certified reference materialpharmaceutical secondary standard
Quality Level:
300
Agency:
traceable to Ph. Eur. P2670000traceable to USP 1554603
API family:
praziquantel
CofA:
current certificate can be downloaded
technique(s):
HPLC: suitablegas chromatography (GC): suitable
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4