Thermo Scientific™ Sodium Dodecyl Sulfate (SDS), C12

Description

• Thermo Scientific™ Sodium Dodecyl Sulfate (C12) is a highly purified form of SDS that is especially suited for protein experiments requiring tightly controlled solubility parameters
• Sodium dodecyl sulfate (SDS) is an alkyl sulfate, anionic detergent used frequently in protein electrophoresis and protein solubilization methods
• It is a component of many cell lysis buffer formulations, including RIPA buffer
• Typical SDS or lauryl sulfate preparations are mixture of several different chain lengths (C10 to C18)
• However, protein renaturation and other specialized methods require very specific surfactant and buffer conditions
• This particular formulation of SDS is highly purified to eliminate nearly all secondary chain lengths besides C12
• Highlights: Popular anionic detergent for protein electrophoresis and solubilization Component of many cell lysis buffer formulations Specially purified formulation is >98% C12 alkyl sulfate Contains low levels of hexadecyl sulfate (C16), which inhibits protein renaturation Detergent properties (pure C12): Molecular Weight: 288.5 Detergent Class: Ionic (anionic) Aggregation Number: 62 Micelle Molecular Weight: 18,000 Critical Micelle Concentration (CMC): 6 to 8mM (0.1728 to 0.2304%, w/v) Cloud Point: >100°C Dialyzable: No