RAB0178
Human Fas Ligand ELISA Kit
for serum, plasma, and cell culture supernatants
Manufacturer: Sigma Aldrich
Synonym(S): FasL
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 KIT | RAB0178-1-KIT | In Stock | ₹ 66,133.80 |
RAB0178 - 1 KIT
In Stock
Quantity
1
Base Price: ₹ 66,133.80
GST (18%): ₹ 11,904.084
Total Price: ₹ 78,037.884
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitablecapture ELISA: suitable
input
sample type plasmasample type serumsample type cell culture supernatant(s)
assay range
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 2 pg/mLstandard curve range: 1.37-1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FASLG(356)
Related Products
Description
- General description: The Human Fas Ligand ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Fas Ligand in serum, plasma, cell culture supernatants and urine.
- Immunogen: Recombinant Human Fas Ligand
- Application: For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
- Biochem/physiol Actions: Binding of Fas Ligand (FasL) to Fas receptor triggers apoptosis in Fas-bearing cells. FasL has the ability to kill T cells and activate B cells which leads to down-regulation of the immune response.[1][2] The mechanism of Fas induced apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD (Fas-associated protein with death domain) followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to eventual cell death.[3] FasL is also involved in AGE (advanced glycation end-product)-mediated apoptosis in human retinal ARPE-19 cells, suggesting its role in diabetic retinopathy.[4] Changes in the activity of FasL suppress normal apoptosis, leading to abnormal survival and growth of tumor cells.[5] Mutations in the FasL gene causes autoimmune lymphoproliferative syndrome (ALPS).[6]
- Other Notes: A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
WGK
WGK 3
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species reactivity: human
packaging: kit of 96 wells (12 strips x 8 wells)
technique(s): ELISA: suitablecapture ELISA: suitable
input: sample type plasmasample type serumsample type cell culture supernatant(s)
assay range: inter-assay cv: <12%intra-assay cv: <10%sensitivity: 2 pg/mLstandard curve range: 1.37-1000 pg/mL
detection method: colorimetric
shipped in: wet ice
storage temp.: −20°C
Gene Information: human ... FASLG(356)
species reactivity:
human
packaging:
kit of 96 wells (12 strips x 8 wells)
technique(s):
ELISA: suitablecapture ELISA: suitable
input:
sample type plasmasample type serumsample type cell culture supernatant(s)
assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 2 pg/mLstandard curve range: 1.37-1000 pg/mL
detection method:
colorimetric
shipped in:
wet ice
storage temp.:
−20°C
Gene Information:
human ... FASLG(356)
species reactivity: rat
packaging: kit of 96 wells (12 strips x 8 wells)
technique(s): ELISA: suitablecapture ELISA: suitable
input: sample type serumsample type plasmasample type cell culture supernatant(s)
assay range: inter-assay cv: <12%intra-assay cv: <10%sensitivity: 90 pg/mLstandard curve range: 82.3-60000 pg/mL
detection method: colorimetric
shipped in: wet ice
storage temp.: −20°C
Gene Information: rat ... Faslg(25385)
species reactivity:
rat
packaging:
kit of 96 wells (12 strips x 8 wells)
technique(s):
ELISA: suitablecapture ELISA: suitable
input:
sample type serumsample type plasmasample type cell culture supernatant(s)
assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 90 pg/mLstandard curve range: 82.3-60000 pg/mL
detection method:
colorimetric
shipped in:
wet ice
storage temp.:
−20°C
Gene Information:
rat ... Faslg(25385)
species reactivity: human
packaging: kit of 96 wells (12 strips x 8 wells)
technique(s): ELISA: suitablecapture ELISA: suitable
input: sample type cell culture supernatant(s)sample type serumsample type urinesample type plasma
assay range: inter-assay cv: <12%intra-assay cv: <10%sensitivity: 4.5 pg/mLstandard curve range: 4.92-1200 pg/mL
detection method: colorimetric
shipped in: wet ice
storage temp.: −20°C
Gene Information: human ... FCER2(2208)
species reactivity:
human
packaging:
kit of 96 wells (12 strips x 8 wells)
technique(s):
ELISA: suitablecapture ELISA: suitable
input:
sample type cell culture supernatant(s)sample type serumsample type urinesample type plasma
assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 4.5 pg/mLstandard curve range: 4.92-1200 pg/mL
detection method:
colorimetric
shipped in:
wet ice
storage temp.:
−20°C
Gene Information:
human ... FCER2(2208)
species reactivity: human
packaging: kit of 96 wells (12 strips x 8 wells)
technique(s): ELISA: suitablecapture ELISA: suitable
input: sample type serumsample type urinesample type plasmasample type cell culture supernatant(s)
assay range: inter-assay cv: <12%intra-assay cv: <10%sensitivity: 85 pg/mLstandard curve range: 78.13-5000 pg/mL
detection method: colorimetric
shipped in: wet ice
storage temp.: −20°C
Gene Information: human ... FCGR2B(2213)
species reactivity:
human
packaging:
kit of 96 wells (12 strips x 8 wells)
technique(s):
ELISA: suitablecapture ELISA: suitable
input:
sample type serumsample type urinesample type plasmasample type cell culture supernatant(s)
assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 85 pg/mLstandard curve range: 78.13-5000 pg/mL
detection method:
colorimetric
shipped in:
wet ice
storage temp.:
−20°C
Gene Information:
human ... FCGR2B(2213)