RAB1590

Human NELL-1 ELISA

Manufacturer: Sigma Aldrich

Select a Size

Pack Size SKU Availability Price
96 WELLS RAB1590-96-WELLS In Stock ₹ 67,365.90

RAB1590 - 96 WELLS

₹ 67,365.90

In Stock

Quantity

1

Base Price: ₹ 67,365.90

GST (18%): ₹ 12,125.862

Total Price: ₹ 79,491.762

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)sample type plasmasample type serum

assay range

inter-assay cv: <12%intra-assay cv: <10%sensitivity: 10 pg/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... NELL1(4745)

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Description

  • General description: The NELL-1 (neural EGFL like 1) gene encodes an extracellular glycoprotein and is mapped to human chromosome 11p15.[1][2] Nell-1 is a 810 amino acids protein containing thrombospondin-1 module at its N-terminus and includes other motifs : five von Willebrand factor C domains and six epidermal growth factor (EGF)-like domains.[3][2]
  • Application: For research use only. Not for use in diagnostic procedures.Please refer to the attached Protocolfor details.
  • Biochem/physiol Actions: NELL-1 (neural EGFL like 1) is associated with the risk of Rhabdomyosarcomas and the gene is identified to be hypomethylated.[4] The protein encoded influences osteogenic related processes and thus loss of the NELL-1 gene function leads to abnormality in bone and cartilage.[3] NELL-1 is considered as a essential factor in skeletal development as it controls the action of runt-related transcription factor 2.[5] Lack of Nell-1 protein decreases the expression of gene encoding cartilage proteins such as collagens, tenascins, matrilins, and chondroadherin. It serves as an important growth factor in promoting regeneration of articular cartilage.[3] NELL-1 is a tumor suppressor gene and hypermethylation of its promoter region indicates poor prognosis of the disease in esophageal adenocarcinoma.[6]
  • Other Notes: A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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species reactivity:
human

packaging:
kit of 96 wells (12 strips x 8 wells)

technique(s):
ELISA: suitable

input:
sample type cell culture supernatant(s)sample type plasmasample type serum

assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 10 pg/ml

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... NELL1(4745)

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human

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kit of 96 wells (12 strips x 8 wells)

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ELISA: suitable

input:
sample type serumsample type plasmasample type cell culture supernatant(s)

assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 12 pg/mLstandard curve range: 12.29-3000 pg/mL

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... NRG1(3084)

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−20°C

Gene Information:
human ... REN(5972)

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input:
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assay range:
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colorimetric

shipped in:
wet ice

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−20°C

Gene Information:
mouse ... Egfr(13649)