G4510

Glutathione−Agarose

lyophilized powder

Manufacturer: Millipore

Synonym(S): Glutathione-Agarose Resin, GSH-agarose, S-linked glutathione agarose

Select a Size

Pack Size SKU Availability Price
1 ML G4510-1-ML In Stock ₹ 9,406.93
5 ML G4510-5-ML In Stock ₹ 34,455.98
10 ML G4510-10-ML In Stock ₹ 48,090.00
50 ML G4510-50-ML In Stock ₹ 1,75,917.08

G4510 - 1 ML

₹ 9,406.93

In Stock

Quantity

1

Base Price: ₹ 9,406.93

GST (18%): ₹ 1,693.247

Total Price: ₹ 11,100.177

form

lyophilized powder

Quality Level

200

analyte chemical class(es)

proteins (GST)

extent of labeling

≥10 μmol per mL gel

technique(s)

immunoprecipitation (IP): suitableprotein purification: suitable

matrix

4% cross-linked beaded agarose

matrix activation

epoxy

matrix attachment

sulfur

matrix spacer

12 atoms (10 carbon)

storage temp.

−20°C

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Description

  • General description: Glutathione S-transferase (GST) is a protein with a molecular weight of 26 KDa that naturally occurs in eukaryotic cells. It belongs to the family of Phase II detoxification enzymes. Glutathione-Agarose consists of glutathione attached through its sulfur to epoxy-activated 4% cross-linked beaded agarose, resulting in a 12-atom (10-carbon) spacer. It is provided as a lyophilized powder stabilized with lactose.
  • Application: Glutathione-Agarose has been used:to purify glutathione S-transferase (GST)-fused protein for generating polyclonal antibody M4Pto incubate supernatant fractions for the purification of full-length p53 (aa 1-393) and its DNA-binding domain (aa 94-288)in affinity purification of the fusion protein
  • Biochem/physiol Actions: Glutathione S-transferases (GSTs), a superfamily of multifunctional detoxification isoenzymes, have a significant role in cellular signaling. GSTs are emerging as promising therapeutic targets due to the overexpression of specific isozymes in various tumors and their potential involvement in the development of other diseases such as neurodegenerative diseases, multiple sclerosis, and asthma.
  • Features and Benefits: Offers rapid, mild, non-denaturing, and highly selective purification of glutathione-binding enzymes.Has a shelf life of two years if stored properly desiccated at -20 °C.Binding capacity: 5-10 mg glutathione S-transferase per mL resin
  • Quantity: One g powder swells to ≥10 ml of gel
  • Physical form: Lyophilized powder stabilized with lactose

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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G4510

lyophilized powder...


form:
lyophilized powder

Quality Level:
200

analyte chemical class(es):
proteins (GST)

extent of labeling:
≥10 μmol per mL gel

technique(s):
immunoprecipitation (IP): suitableprotein purification: suitable

matrix:
4% cross-linked beaded agarose

matrix activation:
epoxy

matrix attachment:
sulfur

matrix spacer:
12 atoms (10 carbon)

storage temp.:
−20°C

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matrix attachment:
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