D4008

Dansylcadaverine

≥97% (TLC)

Manufacturer: Sigma Aldrich

CAS Number: 10121-91-2

Synonym(S): N-(5-Amino­pentyl)-5-di­methyl­amino­naphtha­lene-1-sulfon­amide, N-(Dimethyl­amino­naphtha­lene­sulfonyl)-1,5-pentane­diamine, Monodansyl cadaverine

Select a Size

Pack Size SKU Availability Price
100 MG D4008-100-MG In Stock ₹ 5,194.80
250 MG D4008-250-MG In Stock ₹ 9,867.90
1 G D4008-1-G In Stock ₹ 26,773.20

D4008 - 100 MG

₹ 5,194.80

In Stock

Quantity

1

Base Price: ₹ 5,194.80

GST (18%): ₹ 935.064

Total Price: ₹ 6,129.864

Quality Level

100

Assay

≥97% (TLC)

form

powder

storage temp.

−20°C

SMILES string

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCN

InChI

1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3

InChI key

MLEBFEHOJICQQS-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
50-179-7528
Sigma Aldrich Fine Chemicals Biosciences Dansylcadaverine | 10121-91-2 | MFCD00042704 | 1g
Sigma Aldrich Fine Chemicals Biosciences ₹ 27,356.10
50-179-7529
Sigma Aldrich Fine Chemicals Biosciences Dansylcadaverine >=97% (TLC) | 10121-91-2 | MFCD00042704 | 100MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 5,441.62
50-179-7527
Sigma Aldrich Fine Chemicals Biosciences Dansylcadaverine | 10121-91-2 | MFCD00042704 | 100mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 5,989.20
50-149-0334
AdipoGen Dansylcadaverine, 10121-91-2, 250 mg
AdipoGen ₹ 9,347.43
30432
Dansylcadaverine
Sigma Aldrich ₹ 7,647.90 - ₹ 43,068.00
AR0004OC
1-Naphthalenesulfonamide, N-(5-aminopentyl)-5-(dimethylamino)-
Aaron Chemicals LLC ₹ 598.92 - ₹ 15,828.60
CS-8078
Dansylcadaverine
ChemScene ₹ 8,299.32 - ₹ 1,05,581.04
AA04960
10121-91-2 | 1-Naphthalenesulfonamide, N-(5-aminopentyl)-5-(dimethylamino)-
A2B Chem ₹ 2,310.12 - ₹ 15,400.80

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Description

  • General description: Dansylcadaverine, also called as monodansylcadaverine (MDC), is a lysosomotropic agent. It is present in acidic and lipid rich regions. Dansylcadaverine also acts as a solvent polarity probe.[1] It inhibits vesicular transport and decreases the rotavirus sequestering in L cells, when pre-treated.[2]
  • Application: Dansylcadaverine in methanol has a reported λex of 335 nm and λem of 512 nm. It has been used:as an endocytosis inhibitor in human proximal tubular HK-2 cells,(62) mouse J774A.1 macrophages and human A549 epithelial cells(63) to label autophagic vacuoles in cardiomyocytes for fluorescence microscopy studies(64)in monodansylcadaverine (MDC) staining of fibroblasts in Ankylosing spondylitis (AS) samples(65)
  • Biochem/physiol Actions: The autofluorescent dye dansylcadaverine, or monodansylcadaverine (MDC), is commonly used to monitor autophagy. MDC preferentially accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids.
  • Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
  • Other Notes: Solubility of dansylcadaverine is tested in methanol (10 mg/mL). It has also been reported that dansylcadaverine is soluble in DMSO and acetic acid.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCN

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1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3

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MLEBFEHOJICQQS-UHFFFAOYSA-N

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