E1411

Proline Specific Endopeptidase from Flavobacterium sp.

lyophilized powder, ≥5.0 units/mg solid

Manufacturer: Sigma Aldrich

Synonym(S): EndoProC, Endoprolylpeptidase, Endoproteinase Pro-C, PEPase, Prolyl Endopeptidase

Select a Size

Pack Size SKU Availability Price
50 UNITS E1411-50-UNITS In Stock ₹ 63,458.70

E1411 - 50 UNITS

₹ 63,458.70

In Stock

Quantity

1

Base Price: ₹ 63,458.70

GST (18%): ₹ 11,422.566

Total Price: ₹ 74,881.266

biological source

bacterial (Flavobacterium spp.)

Quality Level

200

form

lyophilized powder

specific activity

≥5.0 units/mg solid

mol wt

~78 kDa

shipped in

dry ice

storage temp.

−20°C

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Description

  • Application: Proline specific endopeptidase is useful for the determination of amino acid sequences of peptides and proteins containing proline residues. Proline specific endopeptidases may be useful in cancer, neurology and diabetes research [1]. Prolyl endopeptidase (PEP) may be used as a drug target for neuropsychiatric diseases such as stress disorder, depression, and schizophrenia [1].
  • Biochem/physiol Actions: An endopeptidase is a proteolytic peptidase that breaks peptide bonds of nonterminal amino acids. Product E1411 is specific for proline (Pro). The Prolyl endopeptidase (PEP) mechanism is thought to be an induced fit mechanism, where the native enzyme exists in a conformationally flexible opened state but is changed to a closed state upon substrate binding [1].
  • Unit Definition: One unit causes the formation of one micromole of p-nitroaniline per minute under specific pH and temperature conditions.
  • Physical form: White amorphous lyophilized powder

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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~78 kDa

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dry ice

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−20°C

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