Description

• General description: α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family.[1]
• Application: α1-Acid glycoprotein from human plasma has been used:as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers[2]to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA[3]to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors[4]
• Biochem/physiol Actions: α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital.[1]
• Preparation Note: Purified from Cohn Fraction VI
• Disclaimer: RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.