Description

• General description: Prepsolv solvents are tailored to the requirements of preparative HPLC to facilitate scale-up from analytical to preparative separations. With their extremely low evaporation residue (<1 mg/l) and low water content, they ensure optimal protection for columns.
• Application: Pharmacokinetic and oral bioavailability study of schaftoside in rats.: This research highlights the use of acetonitrile in chromatographic methods for the pharmacokinetic and bioavailability analysis of schaftoside, providing key insights into its metabolic profile, essential for drug development and clinical studies (Lin et al., 2024). Quantification of mangiferin in streptozotocin-induced diabetic rat plasma using UPLC-MS/MS: Pharmacokinetic assessment of Gentiana rhodantha extract after oral administration.: Demonstrating the utility of acetonitrile in liquid chromatography-mass spectrometry, this study offers a robust method for quantifying natural compounds in biological matrices, crucial for therapeutic evaluations (Zhao and Wu Li, 2024). Lewis base adducts of NpCl(4).: Exploring the coordination chemistry of neptunium(IV) chloride with Lewis bases in acetonitrile, this study advances our understanding of actinide chemistry and its potential applications in nuclear waste management and reprocessing technologies (Lopez et al., 2024). Coordinating nature of M(6)L(12) double-stranded macrocycles: co-ligand competition of perchlorate, water, and acetonitrile depending on metal(II) ions.: Investigating the competitive binding of co-ligands in acetonitrile solutions, this research provides valuable insights into the supramolecular chemistry of macrocyclic compounds, pivotal for the design of molecular sensors and catalysts (An et al., 2024). Pharmacokinetic Properties of Baitouweng Decoction in Bama Miniature Pigs: Implications for Clinical Application in Humans.: Utilizing acetonitrile in the preparation and analysis of traditional Chinese medicine, this study assesses the pharmacokinetics of Baitouweng Decoction, aiding in the translation of its medicinal use from traditional applications to modern clinical practice (Xu et al., 2024).
• Preparation Note: Product filtered through a 0.2 μm filter
• Analysis Note: Purity (GC): ≥ 99.8 %Identity (IR): conformsEvaporation residue: ≤ 1.0 mg/lWater: ≤ 0.05 %Acidity: ≤ 0.0005 meq/gAlkalinity: ≤ 0.0002 meq/gTransmission (at 220 nm): ≥ 90 %Transmission (from 240 nm): ≥ 98 %Filtered by 0.2 µm filter
• Legal Information: PREPSOLV is a trademark of Merck KGaA, Darmstadt, Germany