8.08260

Trifluoroacetic acid

for synthesis

Manufacturer: Sigma Aldrich

CAS Number: 76-05-1

Synonym(S): TFA

Select a Size

Pack Size SKU Availability Price
25 ML 8.08260-25-ML In Stock ₹ 2,930.00
100 ML 8.08260-100-ML In Stock ₹ 6,360.01
8082600521 8.08260-8082600521 In Stock ₹ 6,850.00
500 ML 8.08260-500-ML In Stock ₹ 16,260.01
25 KG 8.08260-25-KG In Stock ₹ 1,35,840.01

8.08260 - 25 ML

₹ 2,930.00

In Stock

Quantity

1

Base Price: ₹ 2,930.00

GST (18%): ₹ 527.40

Total Price: ₹ 3,457.40

vapor density

3.9 (vs air)

Quality Level

200

vapor pressure

97.5 mmHg ( 20 °C)

Assay

≥99% (acidimetric)

form

liquid

refractive index

n20/D 1.3 (lit.)

pH

1 (10 g/L in H2O)

bp

72.4 °C (lit.)

mp

−15.4 °C (lit.)

solubility

soluble 10 g/mL

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Description

  • General description: Trifluoroacetic acid is widely used in organic synthesis as a solvent, catalyst and reagent. It is a strong acid and low boiling point reagent. It can be used as a catalyst for a variety of reactions such as rearrangements, functional group deprotections, oxidations, reductions, condensations, hydroarylations and trifluoromethylations.[1]
  • Application: Trifluoroacetic acid can be used as a catalyst In the direct conversion of cyclohexanone to caprolactam using acetonitrile as the additive.In the synthesis of 1,2,4,5-tetrasubstituted imidazoles by four-component condensation of benzil, aldehydes, amines, and ammonium acetate. Trifluoroacetic acid can also be used In the synthesis of d-α-Tterpineo from d-limonene by Markovnikov addition followed by hydrolysis.
  • Features and Benefits: Trifluoroacetic acid can be used as a catalyst due to its High acidity Easy elimination Good solubility in organic solvent and in water.
  • Analysis Note: Assay (acidimetric): ≥ 99.0 %Density (d 20 °C/ 4 °C): 1.487 - 1.490Identity (IR): passes test

SAFETY INFORMATION

Pictograms

GHS05,GHS07

Signal Word

Danger

Hazard Statements

H314,H332,H412

Precautionary Statements

P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

WGK

WGK 2

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200

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97.5 mmHg ( 20 °C)

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≥99% (acidimetric)

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liquid

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n20/D 1.3 (lit.)

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1 (10 g/L in H2O)

bp:
72.4 °C (lit.)

mp:
−15.4 °C (lit.)

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soluble 10 g/mL

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