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D8375

2-Deoxy-D-glucose

Name: 2-Deoxy-D-glucose | Sigma Aldrich | Chemikart
Brand: Chemikart
Price: 3474.83 inr
Availability: InStock

≥98% (GC), crystalline

Manufacturer: Sigma Aldrich

CAS Number: 154-17-6

Synonym(S): 2-Deoxyglucose, 2-Deoxy-D-arabinohexose

Select a Size

Pack Size	SKU	Availability	Price
10 MG	D8375-10-MG	In Stock	₹ 3,474.83
1 G	D8375-1-G	In Stock	₹ 10,153.85
5 G	D8375-5-G	In Stock	₹ 40,063.33
25 G	D8375-25-G	In Stock	₹ 1,33,504.73
100 G	D8375-100-G	In Stock	₹ 3,55,265.68

D8375 - 10 MG

₹ 3,474.83

In Stock

Quantity

Base Price: ₹ 3,474.83

GST (18%): ₹ 625.469

Total Price: ₹ 4,100.299

biological source

synthetic

Quality Level

200

Assay

≥98% (GC)

form

crystalline

technique(s)

gas chromatography (GC): suitableinhibition assay: suitable

color

white to off-white

mp

146-147 °C (lit.)

solubility

H2O: 0.250 g/5mL

application(s)

clinical researchlife science and biopharmametabolomics

storage temp.

2-8°C

Other Options

Product Name	Manufacturer	Price Range
MilliporeSigma™ Calbiochem™ 2-Deoxy-D-glucose	MilliporeSigma™	₹ 8,224.80
2-Deoxy-D-glucose	Supelco	₹ 43,159.28
2-Deoxy-D-glucose	Sigma Aldrich	₹ 5,585.70 - ₹ 92,261.48
2-Deoxy-D-glucose	Sigma Aldrich	₹ 8,681.65 - ₹ 56,170.93

Description

General description: 2-Deoxy-D-glucose, a non-metabolizable glucose analogue, disrupts glycolysis by targeting hexokinase, the rate-limiting step in glycolysis. Phosphorylated to 2-DG-P by hexokinase, it accumulates in the cell, depleting cellular ATP. This approach, effective in starving and killing cancer cells, may also inhibit virus cells reliant on glycolysis for replication. This versatile molecule finds application in cancer, virology, metabolomics and biochemical research.
Application: 2-Deoxy-D-glucose (2-DG) is used in glucoprivic feeding research to invoke and study the processes of counter-regulatory response (CRR). 2-Deoxy-D-glucose is used in the development of anti-cancer strategies that involve radio- and chemosensitization and oxidative stress.
Biochem/physiol Actions: 2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP. In vitro, 2-Deoxyglucose has been shown to induce autophagy, increase ROS production, and activate AMPK.
Features and Benefits: High-purity compound suitable for a wide variety of research applications
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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synthetic

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200

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≥98% (GC)

form:

crystalline

technique(s):

gas chromatography (GC): suitableinhibition assay: suitable

color:

white to off-white

mp:

146-147 °C (lit.)

solubility:

H2O: 0.250 g/5mL

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clinical researchlife science and biopharmametabolomics

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2-Deoxy-D-glucose

Select a Size

Select a Size

Properties

biological source

Quality Level

Assay

form

technique(s)

color

mp

solubility

application(s)

storage temp.

Other Options

Description

SAFETY INFORMATION

WGK

Flash Point(F)

Flash Point(C)

Personal Protective Equipment

Compare Similar Items

Show Difference

Sigma Aldrich

Sigma Aldrich

biological source: __ Quality Level: 200 Assay: ≥99.9% form: liquid technique(s): __ color: __ mp: __ solubility: __ application(s): __ storage temp.: __

Sigma Aldrich

biological source: bovine articular cartilage Quality Level: 200 Assay: __ form: salt-free, lyophilized powder technique(s): cell culture | mammalian: suitable color: __ mp: __ solubility: PBS: ≥2.00 mg/mL, clear, colorless to yellow application(s): __ storage temp.: −20°C

Sigma Aldrich

biological source: __ Quality Level: 400 Assay: __ form: liquid technique(s): cell culture | mammalian: suitable color: __ mp: __ solubility: __ application(s): __ storage temp.: 2-8°C

biological source:

Quality Level:

200

Assay:

≥99.9%

form:

liquid

technique(s):

color:

mp:

solubility:

application(s):

storage temp.:

__

biological source:

bovine articular cartilage

Quality Level:

200

Assay:

form:

salt-free, lyophilized powder

technique(s):

cell culture | mammalian: suitable

color:

mp:

solubility:

PBS: ≥2.00 mg/mL, clear, colorless to yellow

application(s):

storage temp.:

−20°C

biological source:

Quality Level:

400

Assay:

form:

liquid

technique(s):

cell culture | mammalian: suitable

color:

mp:

solubility:

application(s):

storage temp.:

2-8°C