D6134

2-Deoxy-D-glucose

≥99% (GC), crystalline

Manufacturer: Sigma Aldrich

CAS Number: 154-17-6

Synonym(S): 2-Deoxy-D-arabinohexose

Select a Size

Pack Size SKU Availability Price
250 MG D6134-250-MG In Stock ₹ 5,585.70
1 G D6134-1-G In Stock ₹ 11,050.00
5 G D6134-5-G In Stock ₹ 46,904.73
25 G D6134-25-G In Stock ₹ 92,261.48

D6134 - 250 MG

₹ 5,585.70

In Stock

Quantity

1

Base Price: ₹ 5,585.70

GST (18%): ₹ 1,005.426

Total Price: ₹ 6,591.126

biological source

synthetic (organic)

Quality Level

200

Assay

≥99% (GC)

form

crystalline

technique(s)

gas chromatography (GC): suitable

color

white

mp

146-147 °C (lit.)

solubility

H2O: soluble 330 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)CC=O

Other Options

Image Product Name Manufacturer Price Range
25-972-1GM
MilliporeSigma™ Calbiochem™ 2-Deoxy-D-glucose
MilliporeSigma™ ₹ 8,224.80
PHR9231
2-Deoxy-D-glucose
Supelco ₹ 43,159.28
D8375
2-Deoxy-D-glucose
Sigma Aldrich ₹ 3,474.83 - ₹ 3,55,265.68
D3179
2-Deoxy-D-glucose
Sigma Aldrich ₹ 8,681.65 - ₹ 56,170.93

Description

  • Application: 2-Deoxy-D-glucose (2-DG) is used in glucoprivic feeding research to invoke and study the processes of counter-regulatory response (CRR). 2-Deoxy-D-glucose is used in the development of anti-cancer strategies that involve radio- and chemosensitization and oxidative stress.
  • Biochem/physiol Actions: 2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP. In vitro, 2-Deoxyglucose has been shown to induce autophagy, increase ROS production, and activate AMPK.
  • Preparation Note: A further purification of the Grade II material by recrystallization.
  • Other Notes: To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Cl[H].[H][C@]12C[C@@]3([H])[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C(=O)c4c(O)ccc(Cl)c4[C@H]2O

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