Nafcillin sodium salt monohydrate
Manufacturer: Sigma Aldrich
CAS Number: 7177-50-6
Synonym(S): 6-(2-Ethoxy-1-naphthamido)penicillin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 G | N3269-5-G | In Stock | ₹ 18,413.33 |
N3269 - 5 G
In Stock
Quantity
1
Base Price: ₹ 18,413.33
GST (18%): ₹ 3,314.399
Total Price: ₹ 21,727.729
form
solid
Quality Level
200
antibiotic activity spectrum
Gram-positive bacteria
Mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
O.[Na+].CCOc1ccc2ccccc2c1C(=O)N[C@H]3C4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
InChI
1S/C21H22N2O5S.Na.H2O/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23;;/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27);;1H2/q;+1;/p-1/t15-,16+,19-;;/m1../s1
InChI key
OCXSDHJRMYFTMA-KMFBOIRUSA-M
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Nafcillin sodium salt monohydrate | 7177-50-6 | MFCD01941128 | 5G | Sigma Aldrich Fine Chemicals Biosciences | ₹ 20,542.96 | |
 | Nafcillin sodium | Sigma Aldrich | ₹ 40,756.13 |
Related Products
Description
- General description: Chemical structure: ß-lactam
- Application: Nafcillin sodium is a narrow-spectrum β-lactam antibiotic. It is used to treat infections caused by Gram-positive bacteria, in particular, species of Staphylococci that are resistant to other penicillins. It has been used to study penicillin-binding proteins (PBPs), such as 2a, and heterogeneous expression of methicillin resistance in Staphylococcus aureus[1]. It is a potential therapy of meningitis due to Staphylococcus aureus[2].
- Biochem/physiol Actions: Nafcillin inhibits bacterial cell wall formation by inhibiting PBPs. The irreversible inhibition of the PBPs prevents the final crosslinking (transpeptidation) of the nascent peptidoglycan layer, which disrupts cell wall synthesis.
- Other Notes: 5g
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
form: solid
Quality Level: 200
antibiotic activity spectrum: Gram-positive bacteria
Mode of action: cell wall synthesis | interferes
storage temp.: 2-8°C
SMILES string: O.[Na+].CCOc1ccc2ccccc2c1C(=O)N[C@H]3C4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
InChI: 1S/C21H22N2O5S.Na.H2O/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23;;/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27);;1H2/q;+1;/p-1/t15-,16+,19-;;/m1../s1
InChI key: OCXSDHJRMYFTMA-KMFBOIRUSA-M
form: powder
Quality Level: 200
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: NC(=O)c1cccnc1
InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key: DFPAKSUCGFBDDF-UHFFFAOYSA-N
form: powder
Quality Level: 200
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: NC(=O)c1cccnc1
InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key: DFPAKSUCGFBDDF-UHFFFAOYSA-N
