M6133

7-Methylguanosine 5′-triphosphate sodium salt

≥85% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 104809-18-9

Synonym(S): m7GTP

Select a Size

Pack Size SKU Availability Price
5 MG M6133-5-MG In Stock ₹ 16,648.85
10 MG M6133-10-MG In Stock ₹ 29,422.35
25 MG M6133-25-MG In Stock ₹ 63,878.33

M6133 - 5 MG

₹ 16,648.85

In Stock

Quantity

1

Base Price: ₹ 16,648.85

GST (18%): ₹ 2,996.793

Total Price: ₹ 19,645.643

biological source

natural (inorganic)

Quality Level

200

Assay

≥85% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].C[n+]1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O)c3N=C(N)NC([O-])c13

InChI

1S/C11H20N5O14P3.Na/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22;/h3-4,6-7,9-10,17-18H,2H2,1H3,(H,23,24)(H,25,26)(H3,12,13,14)(H2,20,21,22);/q;+1/p-1/t4-,6-,7-,9?,10-;/m1./s1

InChI key

FSMRTZAMTMQMEF-OCMBMSOASA-M

Other Options

Image Product Name Manufacturer Price Range
AE57236
104809-18-9 | 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
A2B Chem ₹ 12,662.88 - ₹ 32,769.48

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Description

  • General description: 7-Methylguanosine 5′-triphosphate is a mRNA cap structural analog.[1]
  • Application: 7-Methylguanosine 5′-triphosphate (m7GTP) is use to study the structures and mechanisms of eukaryotic cellular mRNA caps in the context of mRNA involvement in protein synthesis. m7GTP may be used to create affinity media for capture and purification of molecules such as eukaryotic initiation factor eIF4E.
  • Biochem/physiol Actions: 7-Methylguanosine 5′-triphosphate (m7GTP) inhibits in vitro protein synthesis by binding to translation initiation complexes.[1] m7GTP is useful to study the structures and mechanisms of eukaryotic cellular mRNA caps in the context of mRNA involvement in protein synthesis.[5] m7GTP has a high affinity for eukaryotic initiation factor eIF4E[1] and may be used to create affinity media for their capture and purification.[6]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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natural (inorganic)

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200

Assay:
≥85% (HPLC)

form:
powder

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−20°C

SMILES string:
[Na+].C[n+]1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O)c3N=C(N)NC([O-])c13

InChI:
1S/C11H20N5O14P3.Na/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22;/h3-4,6-7,9-10,17-18H,2H2,1H3,(H,23,24)(H,25,26)(H3,12,13,14)(H2,20,21,22);/q;+1/p-1/t4-,6-,7-,9?,10-;/m1./s1

InChI key:
FSMRTZAMTMQMEF-OCMBMSOASA-M

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