PHL89745

Oridonin

phyproof® Reference Substance

Manufacturer: Sigma Aldrich

CAS Number: 28957-04-2

Synonym(S): 7a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one, Isodonol

Select a Size

Pack Size SKU Availability Price
10 MG PHL89745-10-MG In Stock ₹ 42,791.23

PHL89745 - 10 MG

₹ 42,791.23

In Stock

Quantity

1

Base Price: ₹ 42,791.23

GST (18%): ₹ 7,702.421

Total Price: ₹ 50,493.651

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥98.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

InChI

1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13+,15+,16-,18+,19-,20+/m0/s1

InChI key

SDHTXBWLVGWJFT-XKCURVIJSA-N

Other Options

Image Product Name Manufacturer Price Range
50-186-5888
Sigma Aldrich Fine Chemicals Biosciences Oridonin >=98% (HPLC), solid | 28957-04-2 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 15,407.64
50-186-5887
Sigma Aldrich Fine Chemicals Biosciences Oridonin >=98% (HPLC), solid | 28957-04-2 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 59,344.42
50-164-5880
Indofine Chemical ORIDONIN, Herbal Standards, 28957-04-2, >98% by HPLC, 20 mg
Indofine Chemical ₹ 16,333.40
50-667-8
Selleck Chemical LLC Oridonin 10mg 28957-04-2 Isodonol, Rubescenin, NSC-250682
Selleck Chemical LLC ₹ 7,187.04
CS-0007086
Oridonin
ChemScene ₹ 2,994.60 - ₹ 48,940.32

Description

  • General description: This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
  • Biochem/physiol Actions: Oridonin has potent anti-tumor activity. Oridonin targets AE (AML1-ETO) oncoprotein. Exposure to oridonin induces apoptosis in AE-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation of AE at D188. The compound also prolonged the lifespan of C57 mice bearing truncated AE-expressing leukemic cells without side effects like suppression of bone marrow or reduction of body weight of animals, and exerted synergic effects while combined with cytosine arabinoside. Additionally, oridonin inhibited tumor growth in nude mice inoculated with t(8;21)-harboring Kasumi-1 cells.
  • Legal Information: phyproof is a registered trademark of PhytoLab GmbH & Co. KG

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

PHL89745

phyproof® Reference Substance...


grade:
primary reference standard

product line:
phyproof® Reference Substance

Assay:
≥98.0% (HPLC)

manufacturer/tradename:
PhytoLab

application(s):
food and beverages

format:
neat

InChI:
1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13+,15+,16-,18+,19-,20+/m0/s1

InChI key:
SDHTXBWLVGWJFT-XKCURVIJSA-N

Img

Sigma Aldrich

PHL89746

phyproof® Reference Substance...


grade:
primary reference standard

product line:
phyproof® Reference Substance

Assay:
≥98.0% (HPLC)

manufacturer/tradename:
PhytoLab

application(s):
__

format:
__

InChI:
1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1

InChI key:
PLAPMLGJVGLZOV-VPRICQMDSA-N

Img

Sigma Aldrich

PHL89747

phyproof® Reference Substance...


grade:
primary reference standard

product line:
phyproof® Reference Substance

Assay:
≥95.0% (HPLC)

manufacturer/tradename:
PhytoLab

application(s):
__

format:
__

InChI:
1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3

InChI key:
MBRLOUHOWLUMFF-UHFFFAOYSA-N

Img

Sigma Aldrich

PHL89748

phyproof® Reference Substance...


grade:
primary reference standard

product line:
phyproof® Reference Substance

Assay:
≥95.0% (HPLC)

manufacturer/tradename:
PhytoLab

application(s):
food and beverages

format:
neat

InChI:
1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1

InChI key:
XVPBINOPNYFXID-LHDUFFHYSA-N