Y0000119
Hydroxycarbamide
European Pharmacopoeia (EP) Reference Standard
Manufacturer: Sigma Aldrich
CAS Number: 127-07-1
Synonym(S): Hydroxyurea, Hydroxycarbamide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 360 MG | Y0000119-360-MG | In Stock | ₹ 14,267.35 |
Y0000119 - 360 MG
In Stock
Quantity
1
Base Price: ₹ 14,267.35
GST (18%): ₹ 2,568.123
Total Price: ₹ 16,835.473
grade
pharmaceutical primary standard
API family
hydroxycarbamide
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
NC(=O)NO
InChI
1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
InChI key
VSNHCAURESNICA-UHFFFAOYSA-N
Gene Information
human ... RRM1(6240) , RRM2(6241) , RRM2B(50484)
Other Options
Related Products
Description
- General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
- Application: Hydroxycarbamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
- Biochem/physiol Actions: Anti-neoplastic. Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.
- Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
- Other Notes: Sales restrictions may apply.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Muta. 1B - Repr. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
grade: pharmaceutical primary standard
API family: hydroxycarbamide
manufacturer/tradename: EDQM
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: NC(=O)NO
InChI: 1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
InChI key: VSNHCAURESNICA-UHFFFAOYSA-N
Gene Information: human ... RRM1(6240) , RRM2(6241) , RRM2B(50484)
grade:
pharmaceutical primary standard
API family:
hydroxycarbamide
manufacturer/tradename:
EDQM
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
NC(=O)NO
InChI:
1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
InChI key:
VSNHCAURESNICA-UHFFFAOYSA-N
Gene Information:
human ... RRM1(6240) , RRM2(6241) , RRM2B(50484)
grade: pharmaceutical primary standard
API family: pidolic acid
manufacturer/tradename: EDQM
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: OC(=O)[C@@H]1CCC(=O)N1
InChI: 1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
InChI key: ODHCTXKNWHHXJC-VKHMYHEASA-N
Gene Information: __
grade:
pharmaceutical primary standard
API family:
pidolic acid
manufacturer/tradename:
EDQM
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
OC(=O)[C@@H]1CCC(=O)N1
InChI:
1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
InChI key:
ODHCTXKNWHHXJC-VKHMYHEASA-N
Gene Information:
__
grade: pharmaceutical primary standard
API family: goserelin
manufacturer/tradename: EDQM
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: −20°C
SMILES string: CC(O)=O.CC(C)C[C@H](NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4c[nH]cn4)NC(=O)[C@@H]5CCC(=O)N5)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N6CCC[C@H]6C(=O)NNC(N)=O
InChI: 1S/C59H84N18O14.C2H4O2/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38;1-2(3)4/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90);1H3,(H,3,4)/t38-,39-,40-,41-,42-,43-,44-,45+,46-;/m0./s1
InChI key: IKDXDQDKCZPQSZ-JHYYTBFNSA-N
Gene Information: human ... GNRHR(2798)
grade:
pharmaceutical primary standard
API family:
goserelin
manufacturer/tradename:
EDQM
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
−20°C
SMILES string:
CC(O)=O.CC(C)C[C@H](NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4c[nH]cn4)NC(=O)[C@@H]5CCC(=O)N5)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N6CCC[C@H]6C(=O)NNC(N)=O
InChI:
1S/C59H84N18O14.C2H4O2/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38;1-2(3)4/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90);1H3,(H,3,4)/t38-,39-,40-,41-,42-,43-,44-,45+,46-;/m0./s1
InChI key:
IKDXDQDKCZPQSZ-JHYYTBFNSA-N
Gene Information:
human ... GNRHR(2798)
grade: pharmaceutical primary standard
API family: acebutolol
manufacturer/tradename: EDQM
application(s): pharmaceutical (small molecule)
format: neat
storage temp.: 2-8°C
SMILES string: CCCC(=O)Nc1ccc(O)c(c1)C(C)=O
InChI: 1S/C12H15NO3/c1-3-4-12(16)13-9-5-6-11(15)10(7-9)8(2)14/h5-7,15H,3-4H2,1-2H3,(H,13,16)
InChI key: FGWZEOPEZISTTR-UHFFFAOYSA-N
Gene Information: __
grade:
pharmaceutical primary standard
API family:
acebutolol
manufacturer/tradename:
EDQM
application(s):
pharmaceutical (small molecule)
format:
neat
storage temp.:
2-8°C
SMILES string:
CCCC(=O)Nc1ccc(O)c(c1)C(C)=O
InChI:
1S/C12H15NO3/c1-3-4-12(16)13-9-5-6-11(15)10(7-9)8(2)14/h5-7,15H,3-4H2,1-2H3,(H,13,16)
InChI key:
FGWZEOPEZISTTR-UHFFFAOYSA-N
Gene Information:
__